<2-Dimethylamino-ethyl>-<2-acetoxy-ethyl>-ether | 90227-60-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: <2-Dimethylamino-ethyl>-<2-acetoxy-ethyl>-ether
• 英文别名: 1-acetoxy-2-(2-dimethylamino-ethoxy)-ethane；1-Acetoxy-2-(2-dimethylamino-aethoxy)-aethan；β-Acetoxy-β'-dimethylamino-diaethylaether；2-[2-(Dimethylamino)ethoxy]ethyl acetate
• CAS: 90227-60-4
• 化学式: C₈H₁₇NO₃
• 分子量: 175.228
• InChiKey: KQLFQQBZBFBSOR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  38.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  溴甲烷 、 <2-Dimethylamino-ethyl>-<2-acetoxy-ethyl>-ether 在 苯 作用下， 生成 [2-(2-acetoxy-ethoxy)-ethyl]-trimethyl-ammonium; bromide
  参考文献：
  名称：

  DE432803

  摘要：

  公开号：
• 作为产物：
  描述：

  乙酸酐 、 alkaline earth salt of/the/ methylsulfuric acid 生成 <2-Dimethylamino-ethyl>-<2-acetoxy-ethyl>-ether
  参考文献：
  名称：

  DE432803

  摘要：

  公开号：

文献信息

• NOVEL CONJUGATES OF CC-1065 ANALOGS AND BIFUNCTIONAL LINKERS
  申请人：Beusker Patrick Henry

  公开号：US20130224227A1

  公开（公告）日：2013-08-29

  This invention relates to novel analogs of the DNA-alkylating agent CC-1065 and to their conjugates. Furthermore this invention concerns intermediates for the preparation of said agents and conjugates. The conjugates are designed to release their (multiple) payload after one or more activation steps and/or at a rate and time span controlled by the conjugate in order to selectively deliver and/or controllably release one or more of said DNA alkylating agents. The agents, conjugates, and intermediates can be used to treat an illness that is characterized by undesired (cell) proliferation. As an example, the agents and the conjugates of this invention may be used to treat a tumor.
• Novel Conjugates of CC-1065 Analogs and Bifunctional Linkers
  申请人：SYNTARGA BV

  公开号：US20170274090A1

  公开（公告）日：2017-09-28

  This invention relates to novel analogs of the DNA-alkylating agent CC-1065 and to their conjugates. Furthermore this invention concerns intermediates for the preparation of said agents and conjugates. The conjugates are designed to release their (multiple) payload after one or more activation steps and/or at a rate and time span controlled by the conjugate in order to selectively deliver and/or controllably release one or more of said DNA alkylating agents. The agents, conjugates, and intermediates can be used to treat an illness that is characterized by undesired (cell) proliferation. As an example, the agents and the conjugates of this invention may be used to treat a tumor.
• CURABLE COMPOSITION, CURED SUBSTANCE, OPTICAL MEMBER, AND LENS
  申请人：FUJIFILM Corporation

  公开号：US20220315686A1

  公开（公告）日：2022-10-06

  Provided is a curable composition containing a polymerizable compound represented by General Formula (A), an acylphosphine oxide photopolymerization initiator, and an amine compound. Ar L-Sp-Pol) n Genera Formula (A) Ar represents an n-valent group containing a nitrogen-containing fused aromatic ring satisfying all items (i) to (iii), as a partial structure. (i) The nitrogen-containing fused aromatic ring has a fused ring structure in which two or more 6-membered rings are fused. (ii) The nitrogen-containing fused aromatic ring has at least one nitrogen atom as a ring-constituting atom. (iii) All ring-constituting atoms have p-orbitals, and all the p-orbitals contribute to aromaticity. L and Sp each independently represent a single bond or a divalent linking group, Pol represents a hydrogen atom or a polymerizable group, and n represents 1 or 2. The polymerizable compound represented by General Formula (A) contains at least one polymerizable group.
• US9629924B2
  申请人：——

  公开号：US9629924B2

  公开（公告）日：2017-04-25
• US9815784B2
  申请人：——

  公开号：US9815784B2

  公开（公告）日：2017-11-14