5-carboxymethoxy-6-(3-cyclopentylpropyl)-1-(2-methoxyethyl)-2-methyl-1H-indole-3-carboxylic acid ethyl ester | 898830-28-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 5-carboxymethoxy-6-(3-cyclopentylpropyl)-1-(2-methoxyethyl)-2-methyl-1H-indole-3-carboxylic acid ethyl ester
• 英文别名: 5-Carboxymethoxy-6-(3-cyclopentylpropyl)-1-(2-methoxyethyl)-2-methyl-1H-indol-3-carboxylic acid ethylester；ethyl 5-carboxymethoxy-6-(3-cyclopentylpropyl)-1-(2-methoxyethyl)-2-methyl-1H-indole-3-carboxylate；2-[6-(3-Cyclopentylpropyl)-3-ethoxycarbonyl-1-(2-methoxyethyl)-2-methylindol-5-yl]oxyacetic acid
• CAS: 898830-28-9
• 化学式: C₂₅H₃₅NO₆
• 分子量: 445.556
• InChiKey: MQSNWZAOMBGAEN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  32
• 可旋转键数：
  13
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  87
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• 1H-INDOLE-3-CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS
  申请人：Merck Patent GmbH

  公开号：EP1836187B1

  公开（公告）日：2009-03-04
• 1H-Indole-3-Carboxylic Acid Derivatives And Their Use As Ppar Agonists
  申请人：Adje Nathalie

  公开号：US20080114034A1

  公开（公告）日：2008-05-15

  Compounds of the formula (1): in which A, R 1 , R 2 and R 3 are as defined in the description, the processes for the preparation of these compounds, the uses thereof for the treatment of dyslipidaemia, atherosclerosis and diabetes, and the pharmaceutical compositions comprising them.
• US7754740B2
  申请人：——

  公开号：US7754740B2

  公开（公告）日：2010-07-13