14-[2]naphthyl-tetradecanoic acid | 5690-25-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 14-[2]naphthyl-tetradecanoic acid
• 英文别名: 14-[2]Naphthyl-tetradecansaeure；14-Naphthalen-2-yltetradecanoic acid
• CAS: 5690-25-5
• 化学式: C₂₄H₃₄O₂
• 分子量: 354.533
• InChiKey: COODFQFIDYSWHQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.1
• 重原子数：
  26
• 可旋转键数：
  14
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  10-氯-10-氧代癸酸甲酯 在 氢氧化钾 、 一水合肼 作用下， 反应 2.0h， 生成 14-[2]naphthyl-tetradecanoic acid
  参考文献：
  名称：

  Huisgen; Rietz, Chemische Berichte, 1957, vol. 90, p. 2768,2777

  摘要：

  DOI：

文献信息

• Strains of bacillus thuringiensis
  申请人：PLANT GENETIC SYSTEMS, N.V.

  公开号：EP0382990A1

  公开（公告）日：1990-08-22

  Two new Bacillus thuringiensis strains, which are deposited at the DSM under accession nos. 5131 and 5132, produce crystal proteins during sporulation that are toxic to Coleoptera. The crystal proteins contain 74 kDa and 129 kDa protoxins, respectively, which can yield 67 and 66 kDa toxins, respectively, as trypsin-digestion products. A plant, the genome of which is transformed with a DNA sequence that comes from either one of the strains and that codes for its respective toxin, is resistant to Coleoptera. Each strain, itself, or its crystals, crystal proteins, protoxin or toxin can be used as the active ingredient in an insecticidal composition for combatting Coleoptera.

  两种新的苏云金芽孢杆菌菌株（存于 DSM，登录号分别为 5131 和 5132）在孢子化过程中会产生对鞘翅目昆虫有毒的晶体蛋白。晶体蛋白分别含有 74 kDa 和 129 kDa 的原毒素，作为胰蛋白酶消化产物，可分别产生 67 kDa 和 66 kDa 的毒素。植物的基因组经 DNA 序列转化后，对鞘翅目昆虫具有抗性。每种菌株本身或其晶体、晶体蛋白、原毒素或毒素都可用作防治鞘翅目昆虫的杀虫组合物的活性成分。
• Biological indicator
  申请人：American Sterilizer Company

  公开号：US10011843B2

  公开（公告）日：2018-07-03

  This invention relates to a biological indicator derived from a composition comprising: a host organism comprising a spore forming bacteria; a reporter gene for producing an indicator enzyme; a regulatory gene; and a vehicle for inserting the reporter gene and the regulatory gene in the host organism; the host organism bearing a transposable genetic element in its genome for inserting an insertion sequence in the regulatory gene; the insertion sequence comprising a transposase, a pair of terminal inverted repeat sequences, and at least one open reading frame for expressing the transposase. The vehicle may be taken up by the host organism. The insertion sequence may be inserted in the regulatory gene. The host organism may undergo sporulation to form the biological indicator. A process and an apparatus for using the biological indicator are disclosed.

  本发明涉及一种生物指示剂，其成分包括：由形成孢子的细菌组成的宿主生物；产生指示剂酶的报告基因；调控基因；以及将报告基因和调控基因插入宿主生物的载体；宿主生物的基因组中含有转座遗传因子，用于在调控基因中插入插入序列；插入序列包括转座酶、一对末端倒置重复序列和至少一个用于表达转座酶的开放阅读框。载体可被宿主生物吸收。插入序列可插入调控基因中。宿主生物可进行孢子繁殖以形成生物指示剂。本发明公开了一种使用生物指示剂的工艺和装置。
• Method for detecting Escherichia coli in a sample
  申请人：3M INNOVATIVE PROPERTIES COMPANY

  公开号：US10023898B2

  公开（公告）日：2018-07-17

  A method of detecting Listeria monocytogenes. The method comprises providing a culture device with a selective culture medium and a detection article comprising a first indicator system. The selective culture medium facilitates the growth of Listeria microorganisms. When a Listeria microorganism is detected in a sample contacted with the culture medium, the detection article is contacted with the culture medium to detect Listeria monocytogenes.

  一种检测李斯特菌的方法。该方法包括提供一个带有选择性培养基的培养装置和一个包含第一指示系统的检测物品。选择性培养基有利于李斯特菌微生物的生长。当在与培养基接触的样品中检测到李斯特菌微生物时，检测物品与培养基接触以检测单增李斯特菌。
• Method for detecting a Shigella or Cronobacter microorganism
  申请人：3M INNOVATIVE PROPERTIES COMPANY

  公开号：US10619181B2

  公开（公告）日：2020-04-14

  A method of detecting a Shigella or Cronobacter microorganism. The method comprises providing a culture device with a selective culture medium and a detection article comprising a first indicator system.

  一种检测志贺氏菌或克罗诺斯菌微生物的方法。该方法包括提供一个带有选择性培养基的培养装置和一个包含第一指示系统的检测物品。
• Rapid read-out biological indicator
  申请人：Minnesota Mining and Manufacturing Company to 3M Innovative Properties Company

  公开号：US20030077688A1

  公开（公告）日：2003-04-24

  A rapid method of determining the efficacy of a sterilization cycle, and an indicator adapted to perform such method, comprising subjecting to the sterilization cycle a source of active enzyme having activity which correlates with the viability of a microorganism commonly used to monitor sterilization, and incubating the enzyme source, following the completion of the sterilization cycle, with an effective amount of a substrate system capable of reacting with any residual active enzyme to produce a detectable enzyme-modified product.

  一种快速确定灭菌周期功效的方法，以及一种适用于执行该方法的指示剂，包括将活性酶源置于灭菌周期中，该酶源的活性与通常用于监测灭菌的微生物的活力相关；在灭菌周期完成后，将酶源与有效量的底物系统孵育，该底物系统能够与任何残留的活性酶发生反应，产生可检测的酶修饰产物。