n-octyl 2,3-di-O-benzoyl-β-D-galactofuranoside | 1240496-78-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: n-octyl 2,3-di-O-benzoyl-β-D-galactofuranoside
• CAS: 1240496-78-9
• 化学式: C₂₈H₃₆O₈
• 分子量: 500.589
• InChiKey: OFWQIMQJFSZTON-LKNBFUSASA-N

反应信息

• 作为反应物：
  描述：

  n-octyl 2,3-di-O-benzoyl-β-D-galactofuranoside 在 氯化亚砜 作用下， 以 吡啶 、 二氯甲烷 为溶剂， 生成
  参考文献：
  名称：

  Synthetic UDP-furanoses inhibit the growth of the parasite Leishmania

  摘要：

  The chemical synthesis of UDP-6-NHAc-6-deoxy-Galf was performed and it led to the isolation of both pure anomers. They were then evaluated together with the previously prepared UDP-furanoses for their anti-parasitic properties against Leishmania donovani promastigotes, one of the agents responsible for visceral leishmaniasis. Amongst them, the unnatural 1,2-trans UDP-6-NHAc-Galf demonstrated a high potency in inhibiting the growth of the parasite. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2010.02.020
• 作为产物：
  描述：

  n-octyl 2,3-di-O-benzoyl-5,6-O-isopropylidene-β-D-galactofuranoside 在 水 、 三氟乙酸 作用下， 以 二氯甲烷 为溶剂， 反应 5.0h， 以88%的产率得到n-octyl 2,3-di-O-benzoyl-β-D-galactofuranoside
  参考文献：
  名称：

  Synthetic UDP-furanoses inhibit the growth of the parasite Leishmania

  摘要：

  The chemical synthesis of UDP-6-NHAc-6-deoxy-Galf was performed and it led to the isolation of both pure anomers. They were then evaluated together with the previously prepared UDP-furanoses for their anti-parasitic properties against Leishmania donovani promastigotes, one of the agents responsible for visceral leishmaniasis. Amongst them, the unnatural 1,2-trans UDP-6-NHAc-Galf demonstrated a high potency in inhibiting the growth of the parasite. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2010.02.020