3-(trifluoromethoxy)phenyl-phenyl-selenide | 1439200-47-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 3-(trifluoromethoxy)phenyl-phenyl-selenide
• 英文别名: 1-Phenylselanyl-3-(trifluoromethoxy)benzene；1-phenylselanyl-3-(trifluoromethoxy)benzene
• CAS: 1439200-47-1
• 化学式: C₁₃H₉F₃OSe
• 分子量: 317.169
• InChiKey: RMVOUAHERZCAFW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.24
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  二苯基二硒醚 、 3-(三氟甲氧基)苯硼酸 在 1,10-菲罗啉 、 copper(II) sulfate 、 sodium carbonate 作用下， 以 乙醇 为溶剂， 反应 5.02h， 以98%的产率得到3-(trifluoromethoxy)phenyl-phenyl-selenide
  参考文献：
  名称：

  Copper-catalyzed C–Se coupling of diphenyl diselenide with arylboronic acids at room temperature

  摘要：

  An efficient synthetic protocol for the Cu-catalyzed cross-coupling of diphenyl diselenide and arylboronic acid at room temperature was described. This catalytic system could tolerate a variety of arylboronic acids with only 3 mol % amount of CuSO4 as the catalyst and inexpensive 1,10-phen. H2O as the ligand. Moreover, this catalytic system used environment-friendly EtOH as the solvent and catalytic amount of Na2CO3 (20 mol %) as the base in the air. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.04.124

文献信息

• Copper-catalyzed C–Se coupling of diphenyl diselenide with arylboronic acids at room temperature
  作者：Bo Zheng、Ying Gong、Hua-Jian Xu

  DOI：10.1016/j.tet.2013.04.124

  日期：2013.7

  An efficient synthetic protocol for the Cu-catalyzed cross-coupling of diphenyl diselenide and arylboronic acid at room temperature was described. This catalytic system could tolerate a variety of arylboronic acids with only 3 mol % amount of CuSO4 as the catalyst and inexpensive 1,10-phen. H2O as the ligand. Moreover, this catalytic system used environment-friendly EtOH as the solvent and catalytic amount of Na2CO3 (20 mol %) as the base in the air. (C) 2013 Elsevier Ltd. All rights reserved.