erythro-1-phenyl-1,2-butanediol | 19774-62-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: erythro-1-phenyl-1,2-butanediol
• 英文别名: erythro-1-Phenyl-1,2-butandiol；(1RS,2SR)-1-phenyl-butane-1,2-diol；(1RS,2SR)-1-Phenyl-butan-1,2-diol；(1RS:2SR)-1-Phenyl-butandiol-(1.2)；(+/-)-erythro-1-Phenyl-butandiol-(1.2)；erythro-1-Phenyl-butandiol-(1,2)；(1S,2R)-1-phenylbutane-1,2-diol
• CAS: 19774-62-0；19774-63-1；22607-13-2；143169-27-1；143169-28-2
• 化学式: C₁₀H₁₄O₂
• 分子量: 166.22
• InChiKey: WFSOUGZEVPHHSM-ZJUUUORDSA-N

物化性质

• 沸点：
  140-150 °C(Press: 10 Torr)
• 密度：
  1.097±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1-phenylbut-1-ene 在 碘 、 silver(I) acetate 作用下， 生成 erythro-1-phenyl-1,2-butanediol
  参考文献：
  名称：

  Conformational preferences in diastereomers. V. Hydrogen-bonding systems

  摘要：

  DOI：

  10.1021/jo00830a014

文献信息

• Enantioconvergent transformation of racemic cis-β-alkyl substituted styrene oxides to (R,R) threo diols by microsomal epoxide hydrolase catalysed hydrolysis
  作者：Giuseppe Bellucci、Cinzia Chiappe、Antonio Cordoni

  DOI：10.1016/0957-4166(95)00436-x

  日期：1996.1

  Both enantiomers of cis-β-ethyl, β-n-propyl, β-n-butyl, and β-n-hexyl substituted styrene oxides undergo microsomal epoxide hydrolase catalysed hydration at the (S) carbon to give the corresponding (R,R) threo diols in a > 90% e.e. A complete kinetic resolution of the racemic epoxide is also obtained with the β-ethyl substituted substrate, but not with its higher homologues.

  顺式-β-乙基，β-正丙基，β-正丁基和β-正己基取代的苯乙烯氧化物的两种对映体均在（S）碳上经历微粒体环氧化物水解酶催化的水合反应，得到相应的（R，R ）> 90％ee的苏糖二醇使用β-乙基取代的底物也可获得外消旋环氧化物的完整动力学拆分，但其同系物较高。
• Takeshita, Mitsuhiro; Miura, Masatomo; Unuma, Yukiko, Journal of the Chemical Society. Perkin transactions I, 1993, # 23, p. 2901 - 2906
  作者：Takeshita, Mitsuhiro、Miura, Masatomo、Unuma, Yukiko

  DOI：——

  日期：——
• Catalytic asymmetric dihydroxylation of cis-disubstituted olefins
  作者：Lisa Wang、K. Barry Sharpless

  DOI：10.1021/ja00045a042

  日期：1992.9
• The potential of kernel classification techniques for land use mapping in urban areas using 5m-spatial resolution IRS-1C imagery
  作者：C. C. Kontoes、V. Raptis、M. Lautner、R. Oberstadler

  DOI：10.1080/01431160050145027

  日期：2000.1

  Two techniques, integrating texture and spatial context properties for the classification of fine spatial resolution imagery from the city of Athens (Hellas) have been tested in terms of accuracy and class specificity. Both techniques were kernel based, using an artificial neural network and the kernel reclassification algorithm. The study demonstrated the high potential of the kernel classifiers to discriminate residential categories on 5 m-spatial resolution imagery. The overall accuracy percentages achieved were 73.44% and 74.22% respectively, considering a seven-class classification scheme. The adopted scheme was subset of the nomenclature referred to as `Classification for Land Use Statistics Eurostat's Remote Sensing programme' (CLUSTERS) used by the Statistical Office of the European Communities (EUROSTAT) to map urban and rural environment.
• Conformational preferences in diastereomers. V. Hydrogen-bonding systems
  作者：Charles A. Kingsbury

  DOI：10.1021/jo00830a014

  日期：1970.5