2-(4-Butoxy-3-methoxyphenyl)acetic acid | 122348-10-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2-(4-Butoxy-3-methoxyphenyl)acetic acid
• CAS: 122348-10-1
• 化学式: C₁₃H₁₈O₄
• 分子量: 238.284
• InChiKey: YBKDHTMWIQLHMK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  17
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-(4-Butoxy-3-methoxyphenyl)acetic acid 在 碳酸氢钠 、 三乙胺 作用下， 以 丙酮 为溶剂， 反应 3.5h， 生成 7-(3-Methoxy-4-butoxyphenylacetamido)-3-desacetoxycephalosporanic acid R-sulfoxide
  参考文献：
  名称：

  Synthesis of cephalosporin R-sulfoxides and their antibacterial properties

  摘要：

  DOI：

  10.1007/bf00763665

文献信息

• [EN] TETRAHYDROPROTOBERBINE COMPOUNDS AND USES THEREOF IN THE TREATMENT OF NEUROLOGICAL, PSYCHIATRIC AND NEURODEGENERATIVE DISEASES<br/>[FR] COMPOSÉS TÉTRAHYDROPROTOBERBINES ET LEURS UTILISATIONS DANS LE TRAITEMENT DE MALADIES NEUROLOGIQUES, PSYCHIATRIQUES ET NEURODÉGÉNÉRATIVES
  申请人：MILLER JAMES JACKSON

  公开号：WO2013020229A1

  公开（公告）日：2013-02-14

  Tetrahydroprotoberbine (THPB) compounds and their use in the treatment of neurological, psychiatric and neurodegenerative diseases is provided. The compounds include d-govadine, l-govadine and racemic govadine, as well as d-THPBs of general formula (I). Enantioselective processes for preparing compounds of formula (I), and d- and l-govadine are also provided.(I)

  提供了Tetrahydroprotoberbine (THPB)化合物及其在治疗神经系统、精神疾病和神经退行性疾病中的用途。这些化合物包括d-govadine、l-govadine和racemic govadine，以及通式(I)的d-THPBs。还提供了制备通式(I)化合物和d-、l-govadine的对映选择性过程。(I)
• Deuterated aminocyclohexyl ether compounds and processes for preparing same
  申请人：Chou Ta Hung Doug

  公开号：US20070088075A1

  公开（公告）日：2007-04-19

  This invention is directed to deuterated aminocyclohexyl ether compounds and processes for preparing same and methods of using same.
• DEUTERATED AMINOCYCLOHEXYL ETHER COMPOUNDS AND PROCESSES FOR PREPARING SAME
  申请人：Chou Doug Ta Hung

  公开号：US20100152276A1

  公开（公告）日：2010-06-17

  This invention is directed to deuterated aminocyclohexyl ether compounds and processes for preparing same and methods of using same.
• TETRAHYDROPROTOBERBINE COMPOUNDS AND USES THEREOF IN THE TREATMENT OF NEUROLOGICAL, PSYCHIATRIC AND NEURODEGENERATIVE DISEASES
  申请人：MILLER James Jackson

  公开号：US20150306092A1

  公开（公告）日：2015-10-29

  Tetrahydroprotoberbine (THPB) compounds and their use in the treatment of neurological, psychiatric and neurodegenerative diseases is provided. The compounds include d-govadine, l-govadine and racemic govadine, as well as d-THPBs of general formula (I). Enantioselective processes for preparing compounds of formula (I), and d- and l-govadine are also provided.(I)
• US7705036B2
  申请人：——

  公开号：US7705036B2

  公开（公告）日：2010-04-27