2-<2-Acetoxy-ethyl>-pentansaeure | 102541-13-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-<2-Acetoxy-ethyl>-pentansaeure
• 英文别名: 4-Acetoxy-2-propyl-buttersaeure；2-(2-Acetyloxyethyl)pentanoic acid
• CAS: 102541-13-9
• 化学式: C₉H₁₆O₄
• 分子量: 188.224
• InChiKey: MSBQPRPRUBMXIA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  13
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  乙酸乙烯酯 、 正戊酸 在 二叔丁基过氧化物 作用下， 生成 2-<2-Acetoxy-ethyl>-pentansaeure
  参考文献：
  名称：

  Nikishin,G.N. et al., Doklady Chemistry, 1961, vol. 138, p. 498 - 501

  摘要：

  DOI：

文献信息

• NOVEL CONJUGATES OF CC-1065 ANALOGS AND BIFUNCTIONAL LINKERS
  申请人：Beusker Patrick Henry

  公开号：US20130224227A1

  公开（公告）日：2013-08-29

  This invention relates to novel analogs of the DNA-alkylating agent CC-1065 and to their conjugates. Furthermore this invention concerns intermediates for the preparation of said agents and conjugates. The conjugates are designed to release their (multiple) payload after one or more activation steps and/or at a rate and time span controlled by the conjugate in order to selectively deliver and/or controllably release one or more of said DNA alkylating agents. The agents, conjugates, and intermediates can be used to treat an illness that is characterized by undesired (cell) proliferation. As an example, the agents and the conjugates of this invention may be used to treat a tumor.
• Novel Conjugates of CC-1065 Analogs and Bifunctional Linkers
  申请人：SYNTARGA BV

  公开号：US20170274090A1

  公开（公告）日：2017-09-28

  This invention relates to novel analogs of the DNA-alkylating agent CC-1065 and to their conjugates. Furthermore this invention concerns intermediates for the preparation of said agents and conjugates. The conjugates are designed to release their (multiple) payload after one or more activation steps and/or at a rate and time span controlled by the conjugate in order to selectively deliver and/or controllably release one or more of said DNA alkylating agents. The agents, conjugates, and intermediates can be used to treat an illness that is characterized by undesired (cell) proliferation. As an example, the agents and the conjugates of this invention may be used to treat a tumor.
• US9629924B2
  申请人：——

  公开号：US9629924B2

  公开（公告）日：2017-04-25
• Nikishin,G.N. et al., Doklady Chemistry, 1961, vol. 138, p. 498 - 501
  作者：Nikishin,G.N. et al.

  DOI：——

  日期：——