3-maleimidophenyldiphenylphosphine oxide | 1022087-05-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-maleimidophenyldiphenylphosphine oxide
• 英文别名: 1-(3-Diphenylphosphorylphenyl)pyrrole-2,5-dione；1-(3-diphenylphosphorylphenyl)pyrrole-2,5-dione
• CAS: 1022087-05-3
• 化学式: C₂₂H₁₆NO₃P
• 分子量: 373.348
• InChiKey: QBHMMPGINXUHDF-UHFFFAOYSA-N

物化性质

• 沸点：
  611.4±47.0 °C(Predicted)
• 密度：
  1.35±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  27
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  54.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  马来酸酐 、 (3-aminophenyl)diphenylphosphine oxide 在 sodium acetate 、 乙酸酐 作用下， 以 丙酮 为溶剂， 反应 13.0h， 以79%的产率得到3-maleimidophenyldiphenylphosphine oxide
  参考文献：
  名称：

  Triphenylphosphine oxide supported on non-cross-linked maleimide–styrene copolymer: application as a novel Hendrickson reagent

  摘要：

  A new triphenylphosphine oxide reagent linked to a linear maleimide-styrene copolymer is synthesized. This phosphine-bound copolymer is converted to copolymer-supported triphenylphosphine ditriflate as a novel Hendrickson reagent by treatment with triflic anhydride. This reacts rapidly in various dehydration reactions such as anhydride, ester and amide formation. This linear and soluble support is also easily recovered and recycled several times without loss of efficiency. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.02.001

文献信息

• Triphenylphosphine oxide supported on non-cross-linked maleimide–styrene copolymer: application as a novel Hendrickson reagent
  作者：Hossein Mahdavi、Javad Amani

  DOI：10.1016/j.tetlet.2008.02.001

  日期：2008.3

  A new triphenylphosphine oxide reagent linked to a linear maleimide-styrene copolymer is synthesized. This phosphine-bound copolymer is converted to copolymer-supported triphenylphosphine ditriflate as a novel Hendrickson reagent by treatment with triflic anhydride. This reacts rapidly in various dehydration reactions such as anhydride, ester and amide formation. This linear and soluble support is also easily recovered and recycled several times without loss of efficiency. (C) 2008 Elsevier Ltd. All rights reserved.