(3R)-tridec-12-en-3-ol | 1187821-69-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (3R)-tridec-12-en-3-ol
• CAS: 1187821-69-7
• 化学式: C₁₃H₂₆O
• 分子量: 198.349
• InChiKey: KEVNZZJIQZUYFE-CYBMUJFWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  14
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  10-十一烯醛 、 diethylzinc 在 (1S,2R,4R)-7,7-dimethyl-1-morpholin-4-yl-bicyclo[2.2.1]heptan-2-ol 、 氯化铵 作用下， 以 正己烷 、 水 为溶剂， 反应 0.25h， 以90%的产率得到(3R)-tridec-12-en-3-ol
  参考文献：
  名称：

  Asymmetric addition of diethylzinc to aldehydes catalyzed by a camphor-derived β-amino alcohol

  摘要：

  The asymmetric addition of diethylzinc to aromatic and aliphatic aldehydes, including linear aliphatic ones,catalyzed by 2 mol % of beta-amino alcohol (1S,2R)-7,7-dimethyl-1-morpholin-4-yl-bicyclo[2.2.1]heptan-2-ol 10 gave the corresponding secondary alcohols in high yields and with up to 94% ee at ambient temperature after 15 min. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2009.06.009

文献信息

• Asymmetric addition of diethylzinc to aldehydes catalyzed by a camphor-derived β-amino alcohol
  作者：Zhi-Long Wu、Hsyueh-Liang Wu、Ping-Yu Wu、Biing-Jiun Uang

  DOI：10.1016/j.tetasy.2009.06.009

  日期：2009.7

  The asymmetric addition of diethylzinc to aromatic and aliphatic aldehydes, including linear aliphatic ones,catalyzed by 2 mol % of beta-amino alcohol (1S,2R)-7,7-dimethyl-1-morpholin-4-yl-bicyclo[2.2.1]heptan-2-ol 10 gave the corresponding secondary alcohols in high yields and with up to 94% ee at ambient temperature after 15 min. (C) 2009 Elsevier Ltd. All rights reserved.