| 1376554-63-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• CAS: 1376554-63-0
• 化学式: C₂₇H₃₂O₅
• 分子量: 436.548
• InChiKey: BVFSCMMTVZNJBK-IZIBRLFBSA-N

反应信息

• 作为反应物：
  描述：

  在 sodiumsulfide nonahydrate 、 三乙胺 作用下， 以 二氯甲烷 、 N,N-二甲基甲酰胺 为溶剂， 反应 2.0h， 生成 1,5-anhydro-6-deoxy-2,3,4-tri-O-benzyl-5-thio-D-altritol
  参考文献：
  名称：

  Convenient one-pot synthesis of thiosugars and their efficient conversion to polyoxygenated cycloalkenes

  摘要：

  A convenient synthesis of polyoxygenated tetrahydrothiopyrans and thiepanes from various alditol derivatives with xylo, ribo, manno, gluco, galacto, and fuco configurations is described. The preparation started from the corresponding partially protected alditols and proceeded in a 'one-pot' manner to afford the final products in 80%-95% yield. Furthermore, thiosugar compounds 2b, 2d, and 2g were converted to the optically pure polyoxygenated cycloalkenes through Ramberg-Backlund reaction in moderate to good overall yield. The procedures can be used for the preparation of polyoxygenated thiosugars and cycloalkenes on a relatively large scale. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2012.03.086