1,2,3,6,7,8-hexahydro-3-(hydroxyimino)-N,N,7-trimethyl-2-oxobenzo[2,1-b:3,4-c']dipyrrole-5-sulfonamide monohydrochloride | 147734-26-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 1,2,3,6,7,8-hexahydro-3-(hydroxyimino)-N,N,7-trimethyl-2-oxobenzo[2,1-b:3,4-c']dipyrrole-5-sulfonamide monohydrochloride
• 英文别名: 3-(hydroxyamino)-N,N,7-trimethyl-2-oxo-6,8-dihydropyrrolo[3,4-g]indole-5-sulfonamide;hydrochloride
• CAS: 147734-26-7
• 化学式: C₁₃H₁₆N₄O₄S*ClH
• 分子量: 360.821
• InChiKey: OOZCDWCDODEXNX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.43
• 重原子数：
  23
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  111
• 氢给体数：
  3
• 氢受体数：
  7

文献信息

• Excitatory amino acid inhibitors for treating sensitive skins
  申请人：Societe L'OREAL S.A.

  公开号：US20030202994A1

  公开（公告）日：2003-10-30

  Sensitive human skin/scalp/mucous membrane conditions, for example skin irritation and/or dry patches and/or erythemas and/or dysaesthesic sensations and/or sensations of heating and/or pruritus, are therapeutically treated by topically applying thereto an effective condition-alleviating amount of at least one inhibitor of at least one excitatory amino acid.

  敏感的人体皮肤/头皮/粘膜状况，例如皮肤刺激和/或干斑和/或红斑和/或痛觉和/或发热感和/或瘙痒，可通过局部使用有效缓解状况的至少一种兴奋性氨基酸抑制剂来治疗。
• Novel isatinoxime derivatives, their preparation and use
  申请人：NEUROSEARCH A/S

  公开号：EP0529636B1

  公开（公告）日：1999-06-23
• Utilisation d'un inhibiteur d'acides aminés excitateurs dans une composition cosmétique ou dermatologique pour peaux sensibles et composition obtenue
  申请人：L'ORÉAL

  公开号：EP0904777B1

  公开（公告）日：2008-11-26
• EXCITATORY AMINO ACID INHIBITORS FOR TREATING SENSITIVE SKINS
  申请人：Breton Lionel

  公开号：US20100004311A1

  公开（公告）日：2010-01-07

  Sensitive human skin/scalp/mucous membrane conditions, for example skin irritation and/or dry patches and/or erythemas and/or dysaesthesic sensations and/or sensations of heating and/or pruritus, are therapeutically treated by topically applying thereto an effective condition-alleviating amount of at least one inhibitor of at least one excitatory amino acid.
• US5242918A
  申请人：——

  公开号：US5242918A

  公开（公告）日：1993-09-07