perfluoro-1,4-dimethyl-2,5-dioxaoctylbenzene | 133414-78-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: perfluoro-1,4-dimethyl-2,5-dioxaoctylbenzene
• 英文别名: [1,2,2,2-Tetrafluoro-1-[1,1,2,3,3,3-hexafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propoxy]ethyl]benzene
• CAS: 133414-78-5
• 化学式: C₁₄H₅F₁₇O₂
• 分子量: 528.165
• InChiKey: CDZRKJDVUDMVBE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.6
• 重原子数：
  33
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  19

反应信息

• 作为产物：
  描述：

  2,5-双(三氟甲基)-3,6-二氧杂十一氟代壬酰氟 在 2,2'-联吡啶 、 碘 、 铜 、 caesium carbonate 、 二甲基亚砜 作用下， 以 二乙二醇二甲醚 为溶剂， 反应 76.0h， 生成 perfluoro-1,4-dimethyl-2,5-dioxaoctylbenzene
  参考文献：
  名称：

  Perfluoroalkylations and perfluorooxaalkylations. Part 2. Copper-mediated cross-coupling of secondary perfluorooxaalkyl iodides and aryl halides [1]

  摘要：

  The first successful application of the copper-mediated cross-coupling reaction using secondary perfluorooxaalkyl iodides and iodoaromatic substrates is described. The yields of the cross-coupled products are optimized by careful choice and control of the experimental conditions. The by-products formed are identified and their probable mode of formation is discussed.

  DOI：

  10.1016/s0022-1139(00)80474-1

文献信息

• Synthesis of aromatic compounds containing perfluoro-oxa-alkyl groups
  作者：Hideo Sawada、Masaharu Nakayama

  DOI：10.1016/s0022-1139(00)80311-5

  日期：1991.1

  Perfluoro-oxa-alkanoyl peroxides[[C3F7O(CF(CF3)CF2O)nCF(CF3)CO2]2, n = 0, 1, 2] smoothly reacted with thiophene and furan under mild conditions to affor 2-perfluoro-oxa-alkylthiophenes and furnas in good yields. Perfluoro-oxa-alkylations of benzene and pyrrole were also found to proceed by the use of these peroxides. Furthermore, these peroxides were found to be applied to direct aromatic perfluoro-oxa-alkylations of polystyrene.