4-Pentylpyridine;hydrochloride | 40089-94-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 4-Pentylpyridine;hydrochloride
• CAS: 40089-94-9
• 化学式: C₁₀H₁₅N*ClH
• 分子量: 185.697
• InChiKey: AUMFFWOHUMLEKS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.76
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  14.1
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  4-吡啶甲醛 在 palladium 10% on activated carbon 、 氢气 作用下， 以 甲醇 、 1,2-二氯乙烷 为溶剂， 反应 4.5h， 生成 α-butyl-4-pyridinemethanol hydrochloride 、 4-Pentylpyridine;hydrochloride
  参考文献：
  名称：

  Controlling chemoselective transformations of 4-acylpyridines via a Pd–C catalytic hydrodechlorination–hydrogenation

  摘要：

  A novel Pd-C catalytic hydrodechlorination-hydrogenation was developed for a multi-step one-pot transformation of 4-acylpyridines. Under the selected conditions, 4-benzoylpyridines and 4-alkanoylpyridines were chemoselectively converted into the corresponding 4-benzylpiperidine hydrochlorides and alpha-alkyl-4-piperidinemethanol hydrochlorides, respectively. This catalytic method was performed simply by an addition of 1 equiv of CICH2CHCl2 to the conventional hydrogenation system and directly gave the crystalline piperidine hydrochlorides in practical quantitative yields. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.12.017

文献信息

• Process for the Preparation of Onium Salts Having a Low Chloride Content
  申请人：Ignatyev Nikolai (Mykola)

  公开号：US20080027230A1

  公开（公告）日：2008-01-31

  The invention relates to a process for the preparation of onium salts having a low chloride content by reaction of an onium chloride with an acid, where the hydrochloric acid forming is removed by azeotropic distillation by coordination to an organic solvent which forms an azeotropic mixture with water.

  本发明涉及一种通过将onium氯化物与酸反应制备低氯化物含量onium盐的方法，其中通过与形成的盐酸协同作用的有机溶剂将其通过共沸蒸馏去除，该有机溶剂与水形成共沸混合物。
• ORAL CARE COMPOSITION CONTAINING IONIC LIQUIDS
  申请人：Colgate-Palmolive Company

  公开号：EP2934469A2

  公开（公告）日：2015-10-28
• [EN] ORAL CARE COMPOSITION CONTAINING IONIC LIQUIDS<br/>[FR] COMPOSITION D'HYGIÈNE BUCCALE CONTENANT DES LIQUIDES IONIQUES
  申请人：COLGATE PALMOLIVE CO

  公开号：WO2014098871A2

  公开（公告）日：2014-06-26

  An oral care composition comprising a compound, wherein the compound comprises: (a) a cation; and (b) an anion, wherein the compound has two or more of (i) an atomic polarizability of from 20 to 60, (ii) a Kier flexibility index of from 2 to 20 and (iii) a molar refractivity of from 3 to 10 is provided.