2-nitroethyl trifluoromethanesulfonate | 132539-94-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: 2-nitroethyl trifluoromethanesulfonate
• CAS: 132539-94-7
• 化学式: C₃H₄F₃NO₅S
• 分子量: 223.13
• InChiKey: SGKDULOMRAIVLU-UHFFFAOYSA-N

物化性质

• 沸点：
  237.1±40.0 °C(Predicted)
• 密度：
  1.657±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  97.6
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  2-<(hydroxyimino)methyl>-1-methylimidazole 、 2-nitroethyl trifluoromethanesulfonate 以45%的产率得到
  参考文献：
  名称：

  GOFF, DANE A.;KOOLPE, GARY A.;KELSON, ANDREW B.;VU, HUYNH M.;TAYLOR, DORR+, J. MED. CHEM., 34,(1991) N, C. 1363-1366

  摘要：

  DOI：
• 作为产物：
  描述：

  2-硝基乙醇 、 三氟甲磺酸酐 在 吡啶 作用下， 以 二氯甲烷 为溶剂， 反应 3.0h， 以28%的产率得到2-nitroethyl trifluoromethanesulfonate
  参考文献：
  名称：

  [EN] HERBICIDALLY ACTIVE 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS AND DERIVATIVES THEREOF
  [FR] COMPOSÉS DE 2-(PHÉNYL SUBSTITUÉ)-CYCLOPENTANE-1,3-DIONE PRÉSENTANT UNE ACTIVITÉ HERBICIDE, ET LEURS DÉRIVÉS

  摘要：

  本发明涉及一种化合物，其化学式为（I）：其中取代基如本文所定义，并且化合物（I）可以选择地以其农药可接受的盐的形式存在。这些化合物被认为适合用作除草剂。因此，本发明还涉及一种控制杂草的方法，特别是在有用植物的作物中控制禾本科杂草，包括将化合物（I）或包含这种化合物的除草剂组合物施用于植物或其生长地点。

  公开号：

  WO2014170413A1

文献信息

• [EN] HERBICIDAL COMPOUNDS<br/>[FR] COMPOSÉS HERBICIDES
  申请人：SYNGENTA PARTICIPATIONS AG

  公开号：WO2016062585A1

  公开（公告）日：2016-04-28

  The present invention relates to a compound of formula (I) wherein: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and G are as defined herein; and wherein the compound of formula (I) is optionally present as an agrochemically acceptable salt thereof. These compounds are thought to be suitable for use as herbicides. The invention therefore also relates to a method of controlling weeds, especially grassy monocotyledonous weeds, in crops of useful plants, comprising applying a compound of formula (I), or a herbicidal composition comprising such a compound, to the plants or to the locus thereof.

  本发明涉及一种化合物，其化学式为（I），其中：其中R1、R2、R3、R4、R5、R6、R7、R8、R9、R10、R11和G如本文所定义；以及其中化合物（I）可作为农药可接受的盐存在。据认为这些化合物适合用作除草剂。因此，本发明还涉及一种控制杂草的方法，特别是在有用植物的作物中控制禾本科杂草，包括将化合物（I）或含有这种化合物的除草剂组合物施用于植物或其生长地点。
• Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof
  申请人：SYNGENTA LIMITED

  公开号：US20160081334A1

  公开（公告）日：2016-03-24

  The present invention relates to a compound of formula (I): wherein the substituents are as defined herein, and wherein the compound of formula (I) is optionally present as an agrochemically acceptable salt thereof. These compounds are thought to be suitable for use as herbicides. The invention therefore also relates to a method of controlling weeds, especially grassy monocotyledonous weeds, in crops of useful plants, comprising applying a compound of formula (I), or a herbicidal composition comprising such a compound, to the plants or to the locus thereof.

  本发明涉及一种式（I）的化合物： 其中取代基如本文所定义，化合物式（I）可以作为农药可接受的盐的形式存在。这些化合物被认为适用于作为除草剂使用。因此，本发明还涉及一种控制有用植物作物中杂草，特别是草本单子叶杂草的方法，包括将式（I）的化合物或包含这样的化合物的除草剂组合物应用于植物或其所在地点。
• Quaternary salts of 2-[(hydroxyimino)methyl]imidazole. 4. Effect of various side-chain substituents on therapeutic activity against anticholinesterase intoxication
  作者：Dane A. Goff、Gary A. Koolpe、Andrew B. Kelson、Huynh M. Vu、Dorris L. Taylor、Clifford D. Bedford、Ralph N. Harris、H. A. Mussalam、Irwin Koplovitz

  DOI：10.1021/jm00108a019

  日期：1991.4

  A series of quaternary salt derivatives of 2-[(hydroxyimino)methyl]-1-methylimidazole incorporating various side chains bearing ether, silyl, nitrile, ester, halogen, nitro, sulfone, amino, or aminosulfonyl substituents was prepared and evaluated in vivo for the treatment of anticholinesterase intoxication. Test results in the mouse revealed that the type and location of the side-chain substituent both have a significant influence on the toxicity and antidotal effectiveness of the compounds. Some of the more active examples represent the most potent therapeutics to date against intoxication by the powerful cholinesterase inhibitors soman and tabun. Significantly, the antidotal effectiveness of the compounds was not dependent on the inhibiting agent nor was there any correlation between in vivo efficacy and in vitro reactivation of ethyl (4-nitrophenyl)methylphosphonate inhibited human acetylcholinesterase. These observations suggested that the main mode of antidotal protection by the compounds is something other than enzyme reactivation.