5,6-bis-hydroxymethyl-7-oxa-bicyclo[2.2.1]hept-2-ene | 115888-24-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四氢呋喃
• 英文名称: 5,6-bis-hydroxymethyl-7-oxa-bicyclo[2.2.1]hept-2-ene
• 英文别名: 5,6-bis-hydroxymethyl-7-oxa-norborn-2-ene；5,6-Bis-hydroxymethyl-7-oxa-norborn-2-en；cis-7-oxabicyclo[2.2.1]hept-5-ene-2,3-dimethanol；7-Oxabicyclo[2.2.1]-5-heptene-2,3-dimethanol；7-Oxabicyclo[2.2.1]-5-hepten-2,3-dimethanol；[3-(Hydroxymethyl)-7-oxabicyclo[2.2.1]hept-5-en-2-yl]methanol
• CAS: 115888-24-9
• 化学式: C₈H₁₂O₃
• 分子量: 156.181
• InChiKey: MOBDXLOZNRUIIF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.7
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  49.7
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  5,6-bis-hydroxymethyl-7-oxa-bicyclo[2.2.1]hept-2-ene 在 镍 、 乙酸乙酯 作用下， 生成 (2-endo,3-exo)-7-oxabicyclo<2.2.1>heptane-2,3-dimethanol
  参考文献：
  名称：

  Riobe; Jolivet, Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1956, vol. 243, p. 164

  摘要：

  DOI：
• 作为产物：
  描述：

  exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride 在 四氢呋喃 、 氢氧化钾 、 lithium aluminium tetrahydride 作用下， 生成 5,6-bis-hydroxymethyl-7-oxa-bicyclo[2.2.1]hept-2-ene
  参考文献：
  名称：

  Riobe; Jolivet, Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1956, vol. 243, p. 164

  摘要：

  DOI：

文献信息

• Method for Preparing Curable Bicyclic Compound Derived from Biomass
  申请人：Korea Institute of Industrial Technology

  公开号：US20140066637A1

  公开（公告）日：2014-03-06

  The present invention relates to a curable bicyclic compound derived from biomass, solvent-free curable composition and a method for preparing thereof. The curable compound derived from biomass according to the invention comprises a bicycle structure, to which one of two epoxide functional groups are bonded.

  本发明涉及一种来自生物质的可固化的双环化合物，无溶剂可固化组合物以及其制备方法。根据本发明，来自生物质的可固化化合物包括一个双环结构，其中一个或两个环氧基团之一与之结合。
• 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs useful
  申请人：E. R. Squibb & Sons, Inc.

  公开号：US04611005A1

  公开（公告）日：1986-09-09

  5,6-Epoxy-7-oxabicycloheptane substituted prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 1 to 5, R is H, lower alkyl, alkali metal or polyhydroxylamine, and R.sup.1 is lower alkyl, aryl, aralkyl, cycloalkyl, cycloalkylalkyl or lower alkenyl, including all stereoisomers thereof. The compounds are cardiovascular agents useful, for example, in the treatment of thrombotic disease.

  提供了具有结构式##STR1##的5,6-环氧-7-氧杂双环庚烷取代前列腺素类似物，其中m为1至5，R为H，低碳烷基，碱金属或多羟胺，R.sup.1为低碳烷基，芳基，芳基烷基，环烷基，环烷基烷基或低烯基，包括所有立体异构体。这些化合物是心血管药物，例如，在治疗血栓性疾病方面很有用。
• Ruthenium complexes, process for preparation thereof, and processes for producing open-ring polymer of cycloolefins and hydrogenation products thereof by using the complex as catalyst
  申请人：Sakamoto Masato

  公开号：US20050014916A1

  公开（公告）日：2005-01-20

  The present invention relates to ruthenium complex compound wherein a heteroatom-containing carbene compound having a six-membered ring structure is bonded to ruthenium and a process for the preparation thereof; a process for producing ring-opened cyclic olefin polymer by subjecting a cyclic olefin to ring-opening metathesis polymerization in the presence of such a ruthenium complex compound; and a process for producing hydrogenated product of ring-opened cyclic olefin polymers by hydrogenating the carbon-carbon double bonds of the above ring-opened polymers. The invention gives hydrogenated product of ring-opened cyclic olefin polymers having physical properties different from those of hydrogenated product of ring-opened polymers of the prior art. Particularly, the use of dicyclopentadiene can give a hydrogenated product of ring-opened cyclic olefin polymer excellent in heat resistance, and this product can be advantageously used as parts or formed products for medical appliances or electrical components.

  本发明涉及一种钌配合物化合物，其中将具有六元环结构的含杂原子的卡宾化合物与钌结合，以及其制备方法；一种通过在此类钌配合物存在下将环状烯烃经环开环甲硫烯聚合制备环开环环状烯烃聚合物的方法；以及一种通过氢化上述环开环聚合物的碳碳双键制备环开环环状烯烃聚合物的氢化产物的方法。该发明提供了具有与先前技术中环开环聚合物氢化产物不同物理性质的环开环环状烯烃聚合物的氢化产物。特别地，使用二环戊二烯可以得到热性能优异的环开环环状烯烃聚合物的氢化产物，该产品可有利地用作医疗器械或电子元件的零部件或成型产品。
• 5,6-epoxy-7-oxabicycloheptane substituted ethers useful in the treatment
  申请人：E. R. Squibb & Sons, Inc.

  公开号：US04611006A1

  公开（公告）日：1986-09-09

  5,6-Epoxy-7-oxabicycloheptane substituted ether prostaglandin analogs are provided having the structural formula ##STR1## wherein X is O or ##STR2## and including all stereoisomers thereof. The compounds are cardiovascular agents useful, for example, in the treatment of thrombotic disease.

  提供了具有结构式##STR1##的5,6-环氧-7-氧代双环庚烷取代醚前列腺素类似物，其中X为O或##STR2##，包括所有立体异构体。这些化合物是心血管药物，例如，在治疗血栓性疾病方面很有用。
• Polymers, resist compositions and patterning process, novel tetrahydrofuran compounds and their preparation
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：US20020197559A1

  公开（公告）日：2002-12-26

  A polymer comprising recurring units of formula (1-1) or (1-2) wherein R 1 , R 2 , R 3 and R 4 are H or alkyl, or R 1 and R 2 , and R 3 and R 4 taken together may form a ring with each pair being alkylene, and k is 0 or 1 and having a Mw of 1,000-500,000 is novel. A resist composition comprising the polymer as a base resin is sensitive to high-energy radiation, has excellent sensitivity, resolution, etching resistance, and minimized swell and lends itself to micropatterning with electron beams or deep-UV. 1

  具有以下公式（1-1）或（1-2）重复单元的聚合物，其中R1、R2、R3和R4为H或烷基，或者R1和R2，以及R3和R4组成的每对可以成为亚烷基环，k为0或1，其Mw为1,000-500,000是新颖的。以该聚合物作为基础树脂的抗蚀剂组合物对高能辐射敏感，具有优异的敏感度、分辨率、蚀刻抗性和最小化膨胀，并适用于电子束或深紫外线微细图案化。