2-oxo-3-(5-oxo-3-(quinolin-4-yl)-2,5-dihydropyrano[3,2-c]chromen-2-yl)-2H-chromen-4-yl acetate | 1360146-05-9

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: 2-oxo-3-(5-oxo-3-(quinolin-4-yl)-2,5-dihydropyrano[3,2-c]chromen-2-yl)-2H-chromen-4-yl acetate
• CAS: 1360146-05-9
• 化学式: C₃₂H₁₉NO₇
• 分子量: 529.505
• InChiKey: BCNGJZXCDWSFOV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.05
• 重原子数：
  40.0
• 可旋转键数：
  3.0
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  108.84
• 氢给体数：
  0.0
• 氢受体数：
  8.0

反应信息

• 作为产物：
  描述：

  4-甲基喹啉 、 4-氯-3-甲酰基香豆素 、 乙酸酐 反应 0.17h， 以52%的产率得到2-oxo-3-(5-oxo-3-(quinolin-4-yl)-2,5-dihydropyrano[3,2-c]chromen-2-yl)-2H-chromen-4-yl acetate
  参考文献：
  名称：

  One-Pot Synthesis of Pyranocoumarins via Microwave-Assisted Pseudo Multicomponent Reactions and Their Molecular Switching Properties

  摘要：

  Two new pyranocoumarins were synthesized via one-pot, microwave-assisted pseudo multicomponent condensations of coumarin and 4-methylquinoline to investigate their molecular switching properties. Both are light-sensitive and have a distinct change of color upon UV irradiation. The reaction can be reverted by treating the photogenerated products with imidazoline-functionalized magnetic nanoparticles, which can be swiftly recycled with an external permanent magnet.

  DOI：

  10.1021/ol203229z