[2-(4-Isopropoxy-phenyl)-ethyl]-methyl-amine | 55384-04-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [2-(4-Isopropoxy-phenyl)-ethyl]-methyl-amine
• 英文别名: 2-(4-Isopropoxyphenyl)-N-methylethan-1-amine；N-methyl-2-(4-propan-2-yloxyphenyl)ethanamine
• CAS: 55384-04-8
• 化学式: C₁₂H₁₉NO
• 分子量: 193.289
• InChiKey: YOIGPTOKOVTYCB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  21.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] SENOTHERAPEUTIC COMPOUND<br/>[FR] COMPOSÉ SÉNOTHÉRAPEUTIQUE
  申请人：BIONEXA S R L

  公开号：WO2022118186A1

  公开（公告）日：2022-06-09

  It is provided a senotherapeutic compound comprising a synthetic derivative of flavones, according to the formula (I), in which at least two of R2-R6 are H, and the remainder are individually selected from: H, OH, R1, OR1, NO2, NH2, NHR1, F, Cl, Br, I, where R1 is a radical.

  提供一种含有黄酮类合成衍生物的治疗化合物，其化学式为(I)，其中R2-R6中至少有两个为H，其余的分别从以下中选择：H，OH，R1，OR1，NO2，NH2，NHR1，F，Cl，Br，I，其中R1是一个基团。
• CHIRALE CYCLOPLATINIERTE KOMPLEXE, HERSTELLUNGSVERFAHREN SOWIE DEREN VERWENDUNG IN MEDIZIN UND KATALYSE
  申请人：Rheinisch-Westfälisch-Technische Hochschule Aachen

  公开号：EP2220100A2

  公开（公告）日：2010-08-25
• BENZOTHIOPHENE ESTROGEN RECEPTOR MODULATORS TO TREAT MEDICAL DISORDERS
  申请人：G1 Therapeutics, Inc.

  公开号：US20210171554A1

  公开（公告）日：2021-06-10

  This invention is a benzothiophene estrogen receptor modulator or its pharmaceutically acceptable salt, N-oxide, isotopic derivative, or prodrug thereof or a pharmaceutically acceptable composition thereof to treat an estrogen-related medical disorder. The invention also includes a combination thereof with another active agent such as a CDK inhibitor, including a CDK4/6 inhibitor, to treat a disorder mediated by the estrogen receptor, as described in more detail herein.
• [DE] VERFAHREN ZUR HERSTELLUNG VON CYCLOPLATINIERTEN PLATIN-KOMPLEXEN, DURCH DIESES VERFAHREN HERGESTELLTE PLATIN-KOMPLEXE SOWIE DEREN VERWENDUNG<br/>[EN] METHOD FOR PRODUCING CYCLOPLATINIZED PLATINUM COMPLEXES, PLATINUM COMPLEXES PRODUCED BY SAID METHOD, AND THE USE THEREOF<br/>[FR] PROCÉDÉ DE PRODUCTION DE COMPLEXES DE PLATINE CYCLOPLATINÉS, COMPLEXE DE PLATINE OBTENU PAR CE PROCÉDÉ ET SON UTILISATION
  申请人：RWTH AACHEN

  公开号：WO2009077462A2

  公开（公告）日：2009-06-25

  Die vorliegende Erfindung betrifft ein Verfahren zur Herstellung von cycloplatinierten Platin(II)-Komplexen, durch dieses Verfahren hergestellte Platin(II)-Komplexe sowie deren Verwendung zur Behandlung von Tumorerkrankungen und/oder Hämoblastosen.
• [EN] PSMA-TARGETED NIR DYES AND THEIR USES<br/>[FR] COLORANTS DU PIR CIBLÉS SUR LE PSMA ET LEURS UTILISATIONS
  申请人：ON TARGET LABORATORIES LLC

  公开号：WO2017044584A1

  公开（公告）日：2017-03-16

  The present disclosure relates to prostate specific membrane antigen (PSMA) targeted compounds conjugated to near-infra red (NIR) dyes and methods for their therapeutic and diagnostic use. More specifically, this disclosure provides compounds and methods for diagnosing and treating diseases associated with cells and/or vasculature expressing prostate specific membrane antigen (PSMA), such as prostate cancer and related diseases. The disclosure further describes methods and compositions for making and using the compounds, methods incorporating the compounds, and kits incorporating the compounds.