2-isopropyl-6-n-propylaniline | 368891-63-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-isopropyl-6-n-propylaniline
• 英文别名: 2-(Propan-2-yl)-6-propylaniline；2-propan-2-yl-6-propylaniline
• CAS: 368891-63-8
• 化学式: C₁₂H₁₉N
• mdl: MFCD20719511
• 分子量: 177.29
• InChiKey: GUTYRTITNMKJBT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  乙酰丙酮 、 2-isopropyl-6-n-propylaniline 在 盐酸 作用下， 以 乙醇 为溶剂， 反应 67.0h， 以36%的产率得到
  参考文献：
  名称：

  Single-Site β-Diiminate Zinc Catalysts for the Alternating Copolymerization of CO₂ and Epoxides:  Catalyst Synthesis and Unprecedented Polymerization Activity

  摘要：

  Synthetic routes to zinc ss -diiminate complexes are reported. The synthesis of 11 ss -diimine [(BDI)H] ligands, with varying N-aryl substituents and bridging structures, is described. These ligands are converted to (BDI)ZnX complexes (X = OAc. Et. N(SiMe3)(2), Br, Cl, OH, OMe, (OPr)-Pr-i). X-ray structural data revealed that all zinc complexes examined exist as mu -X-bridged dimers in the solid state, with the exception of the zinc ethyl and amido complexes which were monomeric. Complexes of the form (BDI)ZnOR (R = alkyl, acyl) and (BDI)ZnN(SiMe3)(2) are highly active catalysts for the alternating copolymerization of epoxides and CO2. Copolymerizations of cyclohexene oxide (CHO) and CO2 with (BDI-1)ZnX [(BDI-1) = 2-((2,6-diisopropylphenyl)amido)-4-((2,6-diisopropylphenyl)imino)-2-pentene)] and (BDI-2)ZnX [(BDI-2) = 2-((2,6-diethylphenyl)amido)-4-((2,6-diethylphenyl)imino)-2-pentene)], where X = OAc, Et, N(SiMe3)(2), Br, Cl, OH, OMe, (OPr)-Pr-i, were attempted at 50 degreesC and 100 Psi CO2. Complexes with X = OAc, N(SiMe3)(2), OMe, (OPr)-Pr-i all produced polycarbonate by the alternated insertion of CHO and CO2 with similar catalytic activities, comparable molecular weights, and narrow molecular weight distributions (MWD similar to 1.1), indicating the copolymerizations are living. Furthermore, ligand effects were shown to dramatically influence the polymerization activity as minor steric changes accelerated or terminated the polymerization activity.

  DOI：

  10.1021/ja003850n
• 作为产物：
  描述：

  2-异丙基苯胺 在 10percent Pd/C 氢气 、 sodium carbonate 、 zinc(II) chloride 作用下， 以 乙醇 、 氯仿 、 xylene 为溶剂， 20.0~80.0 ℃ 、689.49 kPa 条件下， 反应 16.0h， 生成 2-isopropyl-6-n-propylaniline
  参考文献：
  名称：

  Single-Site β-Diiminate Zinc Catalysts for the Alternating Copolymerization of CO₂ and Epoxides:  Catalyst Synthesis and Unprecedented Polymerization Activity

  摘要：

  Synthetic routes to zinc ss -diiminate complexes are reported. The synthesis of 11 ss -diimine [(BDI)H] ligands, with varying N-aryl substituents and bridging structures, is described. These ligands are converted to (BDI)ZnX complexes (X = OAc. Et. N(SiMe3)(2), Br, Cl, OH, OMe, (OPr)-Pr-i). X-ray structural data revealed that all zinc complexes examined exist as mu -X-bridged dimers in the solid state, with the exception of the zinc ethyl and amido complexes which were monomeric. Complexes of the form (BDI)ZnOR (R = alkyl, acyl) and (BDI)ZnN(SiMe3)(2) are highly active catalysts for the alternating copolymerization of epoxides and CO2. Copolymerizations of cyclohexene oxide (CHO) and CO2 with (BDI-1)ZnX [(BDI-1) = 2-((2,6-diisopropylphenyl)amido)-4-((2,6-diisopropylphenyl)imino)-2-pentene)] and (BDI-2)ZnX [(BDI-2) = 2-((2,6-diethylphenyl)amido)-4-((2,6-diethylphenyl)imino)-2-pentene)], where X = OAc, Et, N(SiMe3)(2), Br, Cl, OH, OMe, (OPr)-Pr-i, were attempted at 50 degreesC and 100 Psi CO2. Complexes with X = OAc, N(SiMe3)(2), OMe, (OPr)-Pr-i all produced polycarbonate by the alternated insertion of CHO and CO2 with similar catalytic activities, comparable molecular weights, and narrow molecular weight distributions (MWD similar to 1.1), indicating the copolymerizations are living. Furthermore, ligand effects were shown to dramatically influence the polymerization activity as minor steric changes accelerated or terminated the polymerization activity.

  DOI：

  10.1021/ja003850n

文献信息

• ２，６−ジイソプロピルアニリンの精製方法
  申请人：——

  公开号：JP2005068066A

  公开（公告）日：2005-03-17

  【課題】 ２−イソプロピル−６−ｎ−プロピルアニリン（ＩＮＰＡ）を不純物として含有する２，６−ジイソプロピルアニリン（ＤＩＰＡ）から、ＩＮＰＡ含量の少ない純度の高められたＤＩＰＡを取得するのに好適なＤＩＰＡの精製方法に関する。【解決手段】 ＩＮＰＡ含有のＤＩＰＡを、少なくとも５重量％の水の共存下、イソプロピルアルコールのような有機溶媒中、塩酸塩結晶として回収する。粒状結晶として析出させることにより、高基質濃度での結晶回収操作が可能となる。【選択図】 図１

  一种将含有 2-异丙基-6-正丙基苯胺（INPA）杂质的 2,6-二异丙基苯胺（DIPA）提纯为 INPA 的方法一种提炼 DIPA 的方法，适用于从含有 INPA 杂质的 2,6-二异丙基苯胺 (DIPA) 中获得纯度更高而 INPA 含量更低的 DIPA。含 INPA 的 DIPA 在有机溶剂（如异丙醇）中，在至少 5% 重量的水的存在下，以盐酸盐晶体的形式回收。通过将晶体沉淀为颗粒状晶体，可以在高浓度底物条件下进行晶体回收操作。[选择图] 图 1.
• [EN] RANDOM COPOLYMER AND PRODUCTION PROCESS THEREOF<br/>[FR] COPOLYMÈRE STATISTIQUE ET SON PROCÉDÉ DE FABRICATION
  申请人：SUMITOMO CHEMICAL CO

  公开号：WO2009038006A1

  公开（公告）日：2009-03-26

  A random copolymer comprising two or more kinds of polymerization units represented by the defined formula (1), formula (1) being derived from a diene compound represented by the defined formula (3) such as 2,2-dimethyl-5,5-diallyl-1,3-dioxane; and a process for producing a random copolymer comprising the step of copolymerising two or more kinds of the diene compounds.
• Single-Site β-Diiminate Zinc Catalysts for the Alternating Copolymerization of CO₂ and Epoxides:  Catalyst Synthesis and Unprecedented Polymerization Activity
  作者：Ming Cheng、David R. Moore、Joseph J. Reczek、Bradley M. Chamberlain、Emil B. Lobkovsky、Geoffrey W. Coates

  DOI：10.1021/ja003850n

  日期：2001.9.1

  Synthetic routes to zinc ss -diiminate complexes are reported. The synthesis of 11 ss -diimine [(BDI)H] ligands, with varying N-aryl substituents and bridging structures, is described. These ligands are converted to (BDI)ZnX complexes (X = OAc. Et. N(SiMe3)(2), Br, Cl, OH, OMe, (OPr)-Pr-i). X-ray structural data revealed that all zinc complexes examined exist as mu -X-bridged dimers in the solid state, with the exception of the zinc ethyl and amido complexes which were monomeric. Complexes of the form (BDI)ZnOR (R = alkyl, acyl) and (BDI)ZnN(SiMe3)(2) are highly active catalysts for the alternating copolymerization of epoxides and CO2. Copolymerizations of cyclohexene oxide (CHO) and CO2 with (BDI-1)ZnX [(BDI-1) = 2-((2,6-diisopropylphenyl)amido)-4-((2,6-diisopropylphenyl)imino)-2-pentene)] and (BDI-2)ZnX [(BDI-2) = 2-((2,6-diethylphenyl)amido)-4-((2,6-diethylphenyl)imino)-2-pentene)], where X = OAc, Et, N(SiMe3)(2), Br, Cl, OH, OMe, (OPr)-Pr-i, were attempted at 50 degreesC and 100 Psi CO2. Complexes with X = OAc, N(SiMe3)(2), OMe, (OPr)-Pr-i all produced polycarbonate by the alternated insertion of CHO and CO2 with similar catalytic activities, comparable molecular weights, and narrow molecular weight distributions (MWD similar to 1.1), indicating the copolymerizations are living. Furthermore, ligand effects were shown to dramatically influence the polymerization activity as minor steric changes accelerated or terminated the polymerization activity.