(+/-)-2-methyl-valeric acid ; silver (I)-salt | 95072-13-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (+/-)-2-methyl-valeric acid ; silver (I)-salt
• 英文别名: (+/-)-2-Methyl-valeriansaeure; Silber(I)-Salz；Silver;2-methylpentanoate
• CAS: 95072-13-2
• 化学式: Ag*C₆H₁₁O₂
• 分子量: 223.02
• InChiKey: BDJSQLBLXZGFGZ-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  0.17
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  40.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (+/-)-2-methyl-valeric acid ; silver (I)-salt 在 亚硝酰氯 作用下， 生成 2-Methyl-valerylnitrit
  参考文献：
  名称：

  Pritzkow,W.; Nitzer,H., Journal fur praktische Chemie (Leipzig 1954), 1964, vol. 25, p. 69 - 78

  摘要：

  DOI：

文献信息

• Novel compounds and a novel process for their preparation
  申请人：Fagnou Keith

  公开号：US20050014721A1

  公开（公告）日：2005-01-20

  The present invention is directed to a procedure for making an enantiomerically enriched compound containing a hydronaphthalene ring structure. The process involves reacting oxabenzonorbornadienes with nucleophiles using rhodium as a catalyst and in the presence of a phosphine ligand. The compounds synthesized may be used in pharmaceutical preparations for the treatment of a variety of diseases and conditions.

  本发明涉及一种制备含有氢化萘环结构的对映体富集化合物的方法。该过程涉及使用铑作为催化剂，并在膦配体的存在下，将氧化苯并[2,3-c]环辛二烯与亲核试剂反应。合成的化合物可用于制备治疗各种疾病和病况的药物制剂。
• Novel hydronaphthalene compounds, prepared by a rhodium catalysed ring opening reaction in the presence of phosphine ligand
  申请人：AstraZeneca AB

  公开号：EP1498406A1

  公开（公告）日：2005-01-19

  The present invention is directed to a procedure for making an enantiomerically enriched compound containing a hydronaphthalene ring structure. The process involves reacting oxabenzonorbornadienes with nucleophiles using rhodium as a catalyst and in the presence of a phosphine ligand. The compounds synthesized may be used in pharmaceutical preparations for the treatment of a variety of diseases and conditions.

  本发明涉及一种含有氢萘环结构的对映体富集化合物的制造工艺。该过程包括使用铑作为催化剂，在膦配体存在的情况下，使氧杂苯并降冰片二烯与亲核物反应。合成的化合物可用于治疗各种疾病和病症的药物制剂中。
• NOVEL HYDRONAPHTHALENE COMPOUNDS, PREPARED BY A RHODIUM CATALYZED RING OPENING REACTION IN THE PRESENCE OF PHOSPHINE LIGAND
  申请人：AstraZeneca AB

  公开号：EP1228024B1

  公开（公告）日：2004-09-01
• METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE BY MEANS OF COUPLING METHOD USING A PALLADIUM COMPOUND
  申请人：Teijin Pharma Limited

  公开号：EP2610248B1

  公开（公告）日：2016-06-08
• US6525068B1
  申请人：——

  公开号：US6525068B1

  公开（公告）日：2003-02-25