styryl methanesulfonate | 1444018-13-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: styryl methanesulfonate
• 英文别名: [(E)-2-phenylethenyl] methanesulfonate
• CAS: 1444018-13-6
• 化学式: C₉H₁₀O₃S
• 分子量: 198.243
• InChiKey: MAPAVKAETFJGFW-BQYQJAHWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  51.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  苯乙醛 、 甲基磺酸酐 在 sodium t-butanolate 作用下， 以 四氢呋喃 为溶剂， 反应 3.0h， 以39.394%的产率得到
  参考文献：
  名称：

  铜/钯体系与定制咪唑基膦配体催化的甲磺酸酯的脱羧交叉偶联

  摘要：

  通过使用一类新的咪唑基膦来活化甲磺酸酯中的惰性CO键，可以使甲磺酸甲磺酸酯和多取代的烯基甲磺酸酯进行脱羧偶联。配体的变化导致两种互补方法以良好的产率提供相应的联芳基和多取代的烯烃。

  DOI：

  10.1002/anie.201208025

文献信息

• IMPROVED PROCESS FOR PREPARING MONTELUKAST AND SALTS THEREOF
  申请人：Indukuri Venkata Sunil Kumar

  公开号：US20110112300A1

  公开（公告）日：2011-05-12

  A method for the preparation of montelukast and salts thereof has been described. The method comprises of following steps: (a) (S)-1-(3-((E)-2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-isopropenylphenyljpropyl methane sulphonate (styrene mesylate salt) (b) coupling with 1 -(mercapto methyl)cyclopropane acetic acid followed by salification with an amine gives styrene amine salt (c) Converting styrene amine salt to Montelukast amine salt (d) Converting Montelukast amine salt to Montelukast free acid and or its required alkali/alkaline salt.

  已经描述了一种制备蒙特卢卡斯特及其盐的方法。该方法包括以下步骤：(a) (S)-1-(3-((E)-2-(7-氯喹啉-2-基)乙烯基)苯基)-3-(2-异丙基苯基)丙烷磺酸盐(苯乙烯甲磺酸盐) (b) 与1-(巯基甲基)环丙酸偶联，然后用胺盐化，得到苯乙烯胺盐(c) 将苯乙烯胺盐转化为蒙特卢卡斯特胺盐(d) 将蒙特卢卡斯特胺盐转化为蒙特卢卡斯特游离酸和/或所需的碱/碱性盐。
• PROCESS FOR PREPARING MONTELUKAST AND SALTS THEREOF
  申请人：INDUKURI Venkata Sunil Kumar

  公开号：US20120232276A1

  公开（公告）日：2012-09-13

  A method for the preparation of montelukast and salts thereof has been described. The method comprises of following steps: (a) (S)-1-(3-((E)-2-(7-chloroquinolin-2-yl)vinyliphenyl)-3-(2-isopropenylphenyljpropyl methane sulphonate (styrene mesylate salt) (b) coupling with 1-(mercapto methyl)cyclopropane acetic acid followed by salification with an amine gives styrene amine salt (c) Converting styrene amine salt to Montelukast amine salt (d) Converting Montelukast amine salt to Montelukast free acid and or its required alkali/alkaline salt.

  已经描述了一种制备蒙特卢卡斯特及其盐的方法。该方法包括以下步骤：(a) (S)-1-(3-((E)-2-(7-氯喹啉-2-基)乙烯基苯基)-3-(2-异丙基苯基)丙基甲烷磺酸盐(苯乙烯甲磺酸盐) (b) 与1-(巯基甲基)环丙烷乙酸偶联，然后与胺盐化，得到苯乙烯胺盐(c)将苯乙烯胺盐转化为蒙特卢卡斯特胺盐(d)将蒙特卢卡斯特胺盐转化为蒙特卢卡斯特自由酸及其所需的碱/碱性盐。
• Metal oxide superconducting polymer composites
  申请人：Chien, James C. W.

  公开号：EP0324615A2

  公开（公告）日：1989-07-19

  A process for producing a pattern of metal oxide superconducting (MOS) pathways, that comprise, combining a resist polymer, including polymers of heteroatom aromatic rings (HRP), with compounds of metals by forming a polymer metal complex precursor (PMC); applying said PMC as a layer to a substrate; irradiating the layer with an image of such pattern as by one or more of visible and invisible electromagnetic waves, electron beam, gamma rays and laser beam irradiation. By proper choice of the energy and intensity of the radiation an image is created directly which is superconducting. Other choices of radiation forms a latent image in either positive or negative modes which is then developed by oxygenating the layer at eleva­ted temperature to transform the same into a MOS of super­conducting pathways corresponding to said pattern. Novel superconducting structures particularly useful in semi­conductor integrated circuit and LSIC applications can be produced by this process. The novel heteroatom aromatic ring polymers (HRP) are also useful more generally, as is the generic process of producing superconducting composites of a mixture of metal-oxide superconductor (MOS) with a monomer either with or without catalyst or initiator and with subsequent polymerization, or mixing the MOS with a polymer solution and subsequently removing the solvent.

  一种生产金属氧化物超导（MOS）通路图案的工艺，包括通过形成聚合物金属复合物前体（PMC），将抗蚀聚合物（包括杂原子芳香环聚合物（HRP））与金属化合物结合；将所述 PMC 作为层涂在基底上；通过可见和不可见电磁波、电子束、伽马射线和激光束中的一种或多种照射，用这种图案的图像照射该层。通过适当选择辐射的能量和强度，可直接形成超导图像。其他选择的辐射会形成正或负模式的潜像，然后通过在高温下对该层进行充氧，将其转化为与所述图案相对应的超导通路 MOS。通过这种工艺可以生产出特别适用于半导体集成电路和 LSIC 应用的新型超导结构。新型杂原子芳香环聚合物（HRP）也具有更广泛的用途，就像生产金属氧化物超导体（MOS）与单体混合物的超导复合材料的通用工艺一样，可以使用催化剂或引发剂或不使用催化剂或引发剂，然后进行聚合，或者将 MOS 与聚合物溶液混合，然后除去溶剂。
• Electrophotographic light-sensitive material
  申请人：FUJI PHOTO FILM CO., LTD.

  公开号：EP0416591A2

  公开（公告）日：1991-03-13

  An electrophotographic light-sensitive material comprising a support having provided thereon at least one photoconductive layer containing an inorganic photoconductive substance and a binder resin, wherein the binder resin comprises (A) at least one resin having a weight average molecular weight of from 1 x 103 to 2x 104 and containing not less than 30% by weight of a copolymerizable component corresponding to a repeating unit represented by the general formula (I) described below and having at least one acidic group selected from the group consisting of -P03H2, -SO3H, -COOH, -OH, (wherein R represents a hydrocarbon group or -OR (wherein R represents a hydrocarbon group)) and a cyclic acid anhydride-containing group at one of the terminals of the main chain thereof; wherein a1 and a2 each represents a hydrogen atom, a halogen atom, a cyano group or a hydrocarbon group; and R1 represents a hydrocarbon group; and (B) at least one copolymer having a weight average molecular weight of from 5×104 to 1 x106 and comprising at least a monofunctional macromonomer (M) having a weight average molecular weight of not more than 2×104 and a monomer represented by the general formula (V) described below, the macromonomer (M) comprising at least one polymerizable component corresponding to a repeating unit represented by the general formulae (IVa) and (IVb) described below, and at least one polymerizable component containing at least one acidic group selected from -COOH, -P03H2, -SO3H, -OH, (wherein Ro represents a hydrocarbon group or -ORo (wherein Ro represents a hydrocarbon group)), -CHO, and an acid anhydride-containing group, and the macromonomer (M) having a polymerizable double bond group represented by the general formula (III) described below bonded to only one terminal of the main chain of the polymer; wherein Xo represents -COO-, -OCO-, -CH20CO-, -CH2COO-, -0-, S02-, CO-, -CONHCOO-, CONHCONH-, (wherein R31 represents a hydrogen atom or a hydrocarbon group), and c1 and c2, which may be the same or different, each represents a hydrogen atom, a halogen atom, a cyano group, a hydrocarbon group, -COO-Z1 or -COO-Z1 bonded via a hydrocarbon group (wherein Z1 represents a hydrogen atom or a hydrocarbon group which may be substituted); wherein X1 has the same meaning as Xo in the general formula (III); Q1 represents an aliphatic group having from 1 to 18 carbon atoms or an aromatic group having from 6 to 12 carbon atoms; d1 and d2, which may be the same or different, have the same meaning as c1 and c2 in the general formula (III); and Qo represents -CN, -CONH2, or (wherein Y represents a hydrogen atom, a halogen atom, an alkoxy group or -COOZ2 (wherein Z2 represents an alkyl group, an aralkyl group, or an aryl'group)); wherein X2 has the same meaning as X1 in the general formula (IVa); Q2 has the same meaning as Q1 in the general formula (lVa); and e1 and e2, which may be the same of different, have the same meaning as c1 and c2 in the general formula (III). The electrophotographic light-sensitive material exhibits excellent electrostatic characteristics and mechanical strength even under severe conditions. Also it is advantageously employed in the scanning exposure system using a semiconductor laser beam.

  一种电致发光感光材料，包括一个支撑体，支撑体上至少有一层光电导层，该层含有一种无机光电导物质和一种粘结剂树脂，其中粘结剂树脂包括 (A) 至少一种树脂，该树脂的重量平均分子量为 1 x 103 至 2x 104，并含有不少于 30%（按重量计）的可共聚组分，该组分与下述通式(I)所代表的重复单元相对应，并具有至少一个酸性基团，该酸性基团选自由-P03H2、-SO3H、-COOH、-OH 组成的组、 (其中 R 代表烃基或-OR（其中 R 代表烃基））组成的组中选出，并在其主链的一个末端具有一个含环状酸酐的基团； 其中 a1 和 a2 分别代表氢原子、卤素原子、氰基或烃基；R1 代表烃基；和(B) 至少一种共聚物，其重量平均分子量为 5×104 至 1×106 并至少包括一种单官能团大单体(M)，其重量平均分子量不大于 2×104 和一种由下述通式(V)代表的单体、大单体（M）包括至少一种与下述通式（IVa）和（IVb）所代表的重复单元相对应的可聚合组分，以及至少一种含有至少一种选自-COOH、-P03H2、-SO3H、-OH的酸性基团的可聚合组分、 (其中 Ro 代表烃基或-ORo（其中 Ro 代表烃基））、-CHO 和含酸酐的基团，以及大单体（M）具有仅与聚合物主链的一个末端键合的由下述通式（III）表示的可聚合双键基团； 其中 Xo 代表-COO-、-OCO-、-CH20CO-、-CH2COO-、-0-、S02-、CO-、-CONHCOO-、CONHCONH-、 (其中 R31 代表氢原子或烃基，c1 和 c2 可以相同或不同，各自代表氢原子、卤素原子、氰基、烃基、-COO-Z1 或通过烃基键合的-COO-Z1（其中 Z1 代表氢原子或可被取代的烃基）； 其中 X1 与通式（III）中的 Xo 意义相同；Q1 代表具有 1 至 18 个碳原子的脂肪族基团或具有 6 至 12 个碳原子的芳香族基团；d1 和 d2（可以相同或不同）与通式（III）中的 c1 和 c2 意义相同；以及 Qo 代表-CN、-CONH2 或 Y（其中 Y 代表氢原子）。 (其中 Y 代表氢原子、卤素原子、烷氧基或 -COOZ2（其中 Z2 代表烷基、芳烷基或芳基））； 其中 X2 与通式（IVa）中的 X1 意义相同；Q2 与通式（lVa）中的 Q1 意义相同；e1 和 e2（可以相同或不同）与通式（III）中的 c1 和 c2 意义相同。 这种电子照相感光材料即使在苛刻的条件下也能表现出优异的静电特性和机械强度。此外，在使用半导体激光束的扫描曝光系统中使用这种材料也非常有利。
• A lithographic printing plate precursor of direct image type
  申请人：FUJI PHOTO FILM CO., LTD.

  公开号：EP0530957A1

  公开（公告）日：1993-03-10

  A lithographic printing plate precursor of direct image type, adequately prevented from occurrence of background stains and having excellent printing durability is provided, comprising a base and an image receptive layer provided on the base, in which the image receptive layer contains at least one of the following non-aqueous solvent-dispersed resin grains:    Non-aqueous solvent-dispersed resin grains    Polymer resin grains obtained by (1) subjecting to dispersion polymerization reaction in a non-aqueous solvent, a monofunctional monomer (A) being soluble in the non-aqueous solvent but insoluble after polymerization and containing at least one functional group capable of producing at least one polar group through decomposition and a monofunctional polymer [M] comprising a polymer principal chain containing at least recurring units each containing a silicon atom and/or fluorine atom-containing substituent, to only one end of which a polymerizable double bond group represented by the following General Formula (I) is bonded: wherein V₀ is -O-, -COO-, -OCO-, -CH₂OCO-, -CH₂COO-, -SO₂-, CONCHCOO- or CONHCONH-, (R₁ is a hydrogen atom or a hydrocarbon group containing 1 to 18 carbon atoms), and a₁ and a₂ are, same or different, hydrogen atoms, halogen atoms, cyano groups, hydrocarbon groups, -COO-R₂ or -COO-R₂ via a hydrocarbon group (R₂ is a hydrogen atom or optionally substituted hydrocarbon group).

  本发明提供了一种可充分防止出现背景污点并具有出色印刷耐久性的直接成像型平版印刷板原版，它包括基底和设置在基底上的图像接收层，其中图像接收层包含以下至少一种非水溶剂分散树脂颗粒： 非水溶剂分散树脂颗粒 通过以下方法获得的聚合物树脂颗粒： (1) 在非水溶剂中进行分散聚合反应、可溶于非水溶剂但聚合后不溶的单官能团单体(A)，它含有至少一个官能团，该官能团能通过分解产生至少一个极性基团，以及单官能团聚合物[M]，该聚合物主链含有至少重复单元，每个单元含有一个硅原子和/或含氟原子的取代基，仅在其一端键合有由下通式(I)表示的可聚合双键基团： 其中 V₀ 是-O-、-COO-、-OCO-、-CH₂OCO-、-CH₂COO-、-SO₂-、 CONCHCOO- 或 CONHCONH-，（R₁ 是氢原子或含有 1 至 18 个碳原子的烃基），且 a₁ 和 a₂ 是相同或不同的氢原子、卤素原子、氰基、烃基、-COO-R₂ 或通过烃基的 -COO-R₂（R₂ 是氢原子或任选取代的烃基）。