N,N,N',N'-tetramethylethylenediammonium-bis(propanesulfonate) | 1215825-89-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: N,N,N',N'-tetramethylethylenediammonium-bis(propanesulfonate)
• 英文别名: N,N,N′,N′-tetramethyl-N,N′-bis(3-sulfopropyl)ethylenediaminium；ethane-1,2-bis-N,N-dimethylammonium-N-propanesulfonate
• CAS: 1215825-89-0
• 化学式: C₁₂H₂₈N₂O₆S₂
• 分子量: 360.496
• InChiKey: ICEJRNPSOBYAFL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.99
• 重原子数：
  22.0
• 可旋转键数：
  11.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  114.4
• 氢给体数：
  0.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  N,N,N',N'-tetramethylethylenediammonium-bis(propanesulfonate) 在 磷酸 作用下， 以 水 为溶剂， 反应 8.0h， 生成 N,N,N',N'-tetramethyl-N,N'-bis(3-sulfopropyl)ethylenediaminium bis(dihydrogenphosphate)
  参考文献：
  名称：

  在室温下无溶剂条件下合成1,3,5-三恶烷的简便方法

  摘要：

  摘要以脂肪族多胺和1,3-丙烷磺酸为原料，合成了一系列对环境有益的双-SO 3 H-官能化的布朗斯台德酸性离子液体。这些离子液体在室温下在无溶剂条件下充当脂族醛环三聚的有效廉价且可回收的催化剂。反应进行顺利，分离产率良好至优异（66.9-97.6％=），当离子液体的量为0.1 mol％时，反应通常在1.5小时内完成。离子液体可以容易地回收并重复使用五次，而其催化活性没有任何重大损失。 图形概要

  DOI：

  10.1007/s00706-014-1150-8
• 作为产物：
  描述：

  1,3-丙烷磺内酯 、 四甲基乙二胺 以 甲醇 为溶剂， 反应 20.0h， 以65%的产率得到N,N,N',N'-tetramethylethylenediammonium-bis(propanesulfonate)
  参考文献：
  名称：

  磺基甜菜碱两性离子的水合作用与烷基间隔基长度的关系。

  摘要：

  使用具有同位素取代作用的中子衍射（NDIS）结合使用实测势能结构精化（EPSR）对测得的结构因子进行建模，确定了在浓缩水溶液中包含两个磺基甜菜碱部分的硼状两性离子的溶剂化和结构。在两性离子对的极性体系中观察到强方向的局部水合作用，在每个两性离子对周围的第一个壳水网络中，两性离子分子之间共享48-52个水分子。总体而言，双性两性离子高度水合，为支持在两性离子-水界面上潜在形成抗蛋白质水合层提供了实验证据。

  DOI：

  10.1039/d0cp02654a

文献信息

• Consecutive addition esterification and hydrolysis of cyclic olefins catalyzed by multi-SO₃H functionalized multi heteropolyanion-based ionic hybrids undersolvent-free conditions
  作者：Guocai Zheng、Xinzhong Li

  DOI：10.1080/00397911.2019.1580743

  日期：2019.4.3

  for the synthesis of cycloalkyl carboxylates and alcohols from cyclic olefins is described. The cyclic olefins were converted to corresponding target molecules under solvent-free conditions catalyzed by two novel multi-SO3H functionalized multi heteropolyanion-based ionic hybrids through one-pot consecutive addition esterification and hydrolysis reactions. This approach has several advantages, including

  摘要 描述了从环烯烃合成环烷基羧酸盐和醇的有效方案。环烯烃在无溶剂条件下通过一锅连续加成酯化和水解反应由两种新型多 SO3H 官能化多杂多阴离子基离子杂化物催化转化为相应的目标分子。这种方法有几个优点，包括高产率、简单的后处理和简单的纯化。图形概要
• Efficient production of 5-hydroxymethylfurfural and alkyl levulinate from biomass carbohydrate using ionic liquid-based polyoxometalate salts
  作者：Jinzhu Chen、Guoying Zhao、Limin Chen

  DOI：10.1039/c3ra45632c

  日期：——

  Direct conversion of fructose into 5-hydroxymethylfurfural (HMF) and alkyl levulinate is achieved by making use of ionic liquid-based polyoxometalate salts (IL-POMs) as solid acid catalysts. Among these solid acids, phosphotungstic acid-derived IL-POM shows the highest catalytic performance in both the HMF and ethyl levulinate (EL) formation. A study for optimizing the reaction conditions such as the reaction time and the temperature has been performed. High HMF and EL yields of up to 99% and 82%, respectively, are obtained from fructose under the investigated conditions. Moreover, the generality of the catalyst is further demonstrated by processing representative di- and polysaccharides such as sucrose and inulin with good yields to HMF (76% from inulin and 48% from sucrose) and EL (67% from inulin and 45% from sucrose), again under mild conditions, thereby eliminating the separate hydrolysis step before the dehydration reaction. The catalyst recycling experiment indicates that the adsorption and accumulation of oligomeric products on the catalyst surface results in a partial deactivation of catalyst. The mechanism research reveals that a major pathway for EL formation involves a fructose-to-HMF transformation followed by HMF etherification and rehydration of HMF-ether to give EL. The research highlights an efficient, environment-friendly and recyclable solid acid for biomass valorization.

  果糖直接转化为5-羟甲基糠醛（HMF）和烷基戊酮酸酯通过利用基于离子液体的多金属氧酸盐（IL-POMs）作为固体酸催化剂来实现。在这些固体酸中，源自磷钨酸的IL-POM在HMF和乙基戊酮酸酯（EL）生成中表现出最高的催化性能。已经对反应条件进行优化研究，如反应时间和温度。在所研究的条件下，从果糖获得的HMF和EL的高产率分别可达到99%和82%。此外，催化剂的广泛性通过处理代表性的二糖和多糖，如蔗糖和菊粉，进一步得到证明，在温和条件下，能够良好地转化为HMF（菊粉76%和蔗糖48%）和EL（菊粉67%和蔗糖45%），从而消除了脱水反应前单独水解的步骤。催化剂回收实验表明，寡聚物在催化剂表面的吸附和积累导致催化剂部分失活。机制研究揭示，EL生成的主要路径涉及果糖转化为HMF，随后HMF醚化和HMF醚的再水合生成EL。这项研究突出了用于生物质增值的高效、环保和可回收固体酸催化剂。
• Dicationic ionic liquids as recyclable catalysts for one-pot solvent-free synthesis of α-aminophosphonates
  作者：Dong Fang、Jinming Yang、Chunjie Ni

  DOI：10.1002/hc.20647

  日期：——

  task-specific ionic liquids N,N,N′,N′-tetramethyl-N,N′-dipropanesulfonic acid ethylene-diammonium hydrogen sulfate, N,N,N′,N′-tetramethyl-N,N′-dipropanesulfonic acid-1,3-propanediammonium hydrogen sulfate, N,N,N′,N′- tetramethyl-N,N′- dipropanesulfonic acid-1,6-hexanediammonium hydrogen sulfate were prepared. These ionic liquids could be used as efficient and recyclable catalysts for the synthesis of α-aminophosphonates

  一些特定任务的离子液体 N,N,N',N'-四甲基-N,N'-二丙磺酸 乙二硫酸氢二铵，N,N,N',N'-四甲基-N,N'-二丙磺酸制备了-1,3-丙烷二硫酸氢铵、N,N,N',N'-四甲基-N,N'-二丙磺酸-1,6-己二硫酸氢铵。这些离子液体可用作高效且可回收的催化剂，用于在室温下通过一锅三组分反应在无有机溶剂条件下合成 α-氨基膦酸酯，产率可达 83-96%。后处理简单，催化剂可重复使用至少六次，催化活性不会明显降低。新颖的清洁程序具有反应时间短、产率高、操作简单和环境友好等优点。© 2010 Wiley Periodicals, Inc. 杂原子化学 22:1–5, 2011; 在 wileyonlinelibrary.com 上在线查看这篇文章。DOI 10.1002/hc.20647
• One-pot three-component Biginelli-type reaction catalyzed by ionic liquids in aqueous media
  作者：Dong Fang、Dai-zhen Zhang、Zu-liang Liu

  DOI：10.1007/s00706-010-0271-y

  日期：2010.4

  the first time, 3,4-dihydropyrimidin-2(1H)-one and 3,4-dihydropyrimidin-2(1H)-thione derivatives have been synthesized in good yields by a modified Biginelli-type reaction with dicationic acidic ionic liquids as catalysts. The products could be separated simply from the catalyst–water system, and the catalysts could be reused at least six times without noticeably reducing catalytic activity. Graphical

  摘要首次通过修饰的Biginelli型反应与阳离子酸性离子型化合物以高收率合成了3,4-dihydropyrimidin-2（1 H）-one和3,4-dihydropyrimidin-2（1 H）-硫酮衍生物液体作为催化剂。可以简单地从催化剂-水系统中分离出产物，并且催化剂可以重复使用至少六次，而不会明显降低催化活性。 图形概要
• Solvent-free Baeyer–Villiger oxidation with H2O2 as oxidant catalyzed by multi-SO3H functionalized heteropolyanion-based ionic hybrids
  作者：Xinzhong Li、Rong Cao、Qi Lin

  DOI：10.1016/j.catcom.2014.12.028

  日期：2015.3

  Three novel multi-SO3H functionalized heteropolyanion-based ionic hybrids were synthesized and characterized, which as heterogeneous catalysts for Baeyer-Villiger oxidation using 35% aqueous H2O2 as oxidant show high catalytic activity under solvent-free conditions, the target lactones were obtained with yields of 69% to 88% in 3 h at 50 degrees C. Three ionic hybrids could be recovered readily and their catalytic activity almost completely retained after ten recycles. (C) 2015 Elsevier B.V. All rights reserved.