4-(dipentylamino)benzaldehyde | 313479-64-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(dipentylamino)benzaldehyde
• 英文别名: 4-Dipentylamino-benzaldehyde
• CAS: 313479-64-0
• 化学式: C₁₇H₂₇NO
• 分子量: 261.407
• InChiKey: ZOCJMTAIYKFAEY-UHFFFAOYSA-N

物化性质

• 沸点：
  387.6±25.0 °C(Predicted)
• 密度：
  0.964±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  19
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-(dipentylamino)benzaldehyde 在 sodium t-butanolate 作用下， 以 四氢呋喃 为溶剂， 反应 23.0h， 生成 2,5-dicyano-[1-(p-dipentylamino)styryl-4-(p-amino)styryl]benzene
  参考文献：
  名称：

  Metal Ion Sensing Novel Calix[4]crown Fluoroionophore with a Two-Photon Absorption Property

  摘要：

  1,3-Alternate calix[4] arene-based fluorescent chemosensors bearing two-photon absorbing chromophores have been synthesized, and their sensing behaviors toward metal ions were investigated via absorption band shifts as well as one-and two-photon fluorescence changes. Free ligands absorb the light at 461 nm and weakly emit their fluorescence at 600 nm when excited by UV-vis radiation at 461 nm, but no two-photon excited fluorescence is emitted by excitation at 780 nm. Addition of an Al3+ or Pb2+ ion to a solution of the ligand causes a blue-shifted absorption and enhanced fluorescence due to a declined resonance energy transfer (RET) upon excitation by one-and two-photon processes. Addition of a Pb2+ ion to a solution of 1 center dot K+ results in a higher fluorescence intensity than the original 1 center dot Pb2+ complex regardless of one-or two-photon excitation, due to the allosteric effect induced by the complexation of K+ with a crown loop.

  DOI：

  10.1021/jo0610098
• 作为产物：
  描述：

  1-碘戊烷 在 potassium carbonate 、 三氯氧磷 作用下， 以 乙醇 为溶剂， 反应 22.5h， 生成 4-(dipentylamino)benzaldehyde
  参考文献：
  名称：

  Alkyl substituent effects on J- or H-aggregate formation of bisazomethine dyes

  摘要：

  Bisazomethine dyes with terminal alkyl substituents of different chain lengths (BAR: R = 1, 2, 3, 4, 5 and 6) were synthesized and deposited on a glass substrate to investigate the effect of the alkyl chain length on aggregate formation. Methyl- and ethyl-substituted bisazomethine dyes (BA1 and BA2) formed J-aggregates in thin films (ca. 50 nm), whereas, propyl-, butyl-, pentyl- and hexyl-substituted derivatives (BA3, BA4, BA5 and BA6) formed H-aggregates in thin films (ca. 50 nm). The aggregate formation of the BARs changed drastically between ethyl- and propyl-substituents (BA2/BA3). However, no remarkable changes were observed in the surface morphologies of BA2 and BA3 films. It is suggested that the critical determinant of aggregate formation of BAR is the molecular packing in the film, which depends on the chain length of the terminal alkyl substituent. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.dyepig.2011.05.024

文献信息

• Faster and More Specific: Excited-State Intramolecular Proton Transfer-Based Dyes for High-Fidelity Dynamic Imaging of Lipid Droplets within Cells and Tissues
  作者：Gangwei Jiang、Yi Jin、Man Li、Huiling Wang、Mengyao Xiong、Weili Zeng、Hong Yuan、Changlin Liu、Zhuqing Ren、Chunrong Liu

  DOI：10.1021/acs.analchem.0c00390

  日期：2020.8.4

  first class of excited-state intramolecular proton transfer (ESIPT) fluorescence dyes (Flp-(11–13, 19)) for dynamic imaging of LDs based on 3-hydroxyflavone (3HF) derivatives. Flp-(11–13, 19) display strong fluorescence from yellow to NIR in lipid but exhibit almost nonfluorescence in aqueous solution. Besides, they also show large Stokes shifts (>150 nm), narrow absorption and emission peaks, and good

  脂质滴（LDs）是一种驻留在细胞脂质存储中心的动态细胞器，已经确定在多种生物过程，代谢紊乱和疾病中起重要作用。发现LD的高动态特性与其生理和病理功能相对应。因此，能够动态跟踪LDs的荧光探针对于更好地了解LDs涉及生物过程和疾病的机制应该非常有帮助。在此，我们以我们所知，介绍了用于基于3-羟基黄酮（3HF）的LDs动态成像的第一类激发态分子内质子转移（ESIPT）荧光染料（Flp-（ 11-13，19））衍生品。Flp-（11-13、19）在脂质中显示出从黄色到NIR的强荧光，但在水溶液中几乎不显示荧光。此外，它们还显示出较大的斯托克斯频移（> 150 nm），窄的吸收和发射峰以及良好的油水分离效率，这使其特别针对活细胞和固定细胞中背景噪声极低的LD并对其进行染色。他们以非常低的剂量（低至500 nM）很快（在30 s内）染色细胞内LD。受益于这些优势，Flp-（11-13，19） 已成功
• Oxazolone analogs as amyloid aggregation inhibitors and for the treatment of alzheimer's disease and disorders related to amyloidosis
  申请人：——

  公开号：US20040180943A1

  公开（公告）日：2004-09-16

  Disclosed are compounds of the Formula I 1 and their use in a method of inhibiting the aggregation of amyloid proteins and in a method of imaging amyloid deposits.

  揭示了Formula I1的化合物及其在抑制淀粉样蛋白聚集的方法和成像淀粉样沉积的方法中的应用。
• Pyran derivative, method for manufacturing the same, and light-emitting element containing the pyran derivative
  申请人：Yamagata Sachiko

  公开号：US20050048315A1

  公开（公告）日：2005-03-03

  A light-emitting compound that has excellent carrier transportation properties and that can exhibit long wavelength light is disclosed. Further, a method for manufacturing the light-emitting compound in a high yield is disclosed. The disclosed light-emitting compound is a pyran derivative as represented by general formula 1: wherein A 1 and A 2 are individually a π-conjugated system group having 6 to 16 conjugating carbon atoms; X 1 is a dialkylamino group; and Y 1 is a diarylamino group or an alkylarylamino group.

  揭示了一种具有优异载流子传输性能并能发射长波长光的发光化合物。此外，还揭示了一种高产率制备该发光化合物的方法。所揭示的发光化合物是一种吡喃衍生物，表示为通用式1：其中A1和A2分别是具有6到16个共轭碳原子的π共轭系统基团；X1是二烷基胺基团；Y1是二芳胺基团或烷基芳胺基团。
• 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles
  申请人：Tsubouchi Hidetsugu

  公开号：US20060094767A1

  公开（公告）日：2006-05-04

  The present invention provides a 2,3-dihydro-6-nitroimidazo[2,1-b]oxazole compound represented by the following general formula: wherein R 1 represents a hydrogen atom or C1-C6 alkyl group, n represents an integer of 0 to 6, R 2 represents a group —OR 3 or the like, and R 3 represents a hydrogen atom, C1-C6 alkyl group or the like, or R 1 and —(CH 2 ) n R 2 may bind to each other together with carbon atoms adjacent thereto through nitrogen atoms so as to form a spiro ring represented by the general formula (H): wherein R 41 is hydrogen, C1-C6 alkyl group or the like. The present compound has an excellent bactericidal action against Mycobacterium tuberculosis , multi-drug-resistant Mycobacterium tuberculosis , and atypical acid-fast bacteria.

  本发明提供了一种2,3-二氢-6-硝基咪唑并[2,1-b]噁唑化合物，其通式如下：其中，R1代表氢原子或C1-C6烷基，n代表0到6的整数，R2代表—OR3或类似的基团，R3代表氢原子、C1-C6烷基或类似的基团，或者R1和—(CH2)nR2可以通过相邻的碳原子通过氮原子结合在一起形成一个螺环，其通式为（H）：其中，R41为氢、C1-C6烷基或类似的基团。该化合物对结核分枝杆菌、多药耐药结核分枝杆菌和非典型酸性快速细菌具有优异的杀菌作用。
• Bis (aminostyryl) benzene compunds and synthetic intermediates thereof, and process for preparing the compounds and intermediates
  申请人：——

  公开号：US20030069437A1

  公开（公告）日：2003-04-10

  A bis(aminostyryl)benzene compound of the following general formula [I] is provided 1 wherein R 2 and R 3 independently represent an unsubstituted aryl group, and R 1 and R 4 independently represent an aryl group, and R 5 to R 8 independently represent a cyano group or the like. A process for the preparation thereof is described wherein a 4-(N,N-diarylamino)benzaldehyde and a diphosphonic acid ester or diphosphonium salt are, for example, subjected to condensation reaction. Intermediates of the bis(aminostyryl)benzene compound are also described.

  提供了以下一般式［I］的双(氨基苯乙烯基)苯化合物，其中R2和R3独立地表示未取代的芳基，而R1和R4独立地表示芳基，而R5至R8独立地表示氰基或类似物。其中一种制备方法是将4-(N,N-二芳基氨基)苯甲醛和二膦酸酯或二膦酸盐进行缩合反应。还描述了双(氨基苯乙烯基)苯化合物的中间体。