5-oxo-7-piperidin-1-yl-heptanoic acid | 408308-21-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 5-oxo-7-piperidin-1-yl-heptanoic acid
• 英文别名: 5-oxo-7-piperidino-heptanoic acid；5-Oxo-7-piperidino-heptansaeure；5-Oxo-7-piperidin-1-ylheptanoic acid
• CAS: 408308-21-4
• 化学式: C₁₂H₂₁NO₃
• 分子量: 227.304
• InChiKey: GRWQVRMMTOMKJJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.7
• 重原子数：
  16
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  57.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  5-oxo-7-piperidin-1-yl-heptanoic acid 在 盐酸 作用下， 生成 5-semicarbazono-hept-6-enoic acid methyl ester
  参考文献：
  名称：

  Nasarow; Saw'jalow, Zhurnal Obshchei Khimii, 1953, vol. 23, p. 1703,1710; engl. Ausg. S. 1793, 1799

  摘要：

  DOI：
• 作为产物：
  描述：

  聚合甲醛 、 哌啶盐酸盐 、 5-氧代己酸 生成 5-oxo-7-piperidin-1-yl-heptanoic acid
  参考文献：
  名称：

  Impact processing of chondritic planetesimals: Siderophile and volatile element fractionation in the Chico L chondrite

  摘要：

  Abstract— A large impact event 500 Ma ago shocked and melted portions of the L‐chondrite parent body. Chico is an impact melt breccia produced by this event. Sawn surfaces of this 105 kg meteorite reveal a dike of fine‐grained, clast‐poor impact melt cutting shocked host chondrite. Coarse (1–2 cm diameter) globules of FeNi metal + sulfide are concentrated along the axis of the dike from metal‐poor regions toward the margins. Refractory lithophile element abundance patterns in the melt rock are parallel to average L chondrites, demonstrating near‐total fusion of the L‐chondrite target by the impact and negligible crystal‐liquid fractionation during emplacement and cooling of the dike.Significant geochemical effects of the impact melting event include fractionation of siderophile and chalcophile elements with increasing metal‐silicate heterogeneity, and mobilization of moderately to highly volatile elements. Siderophile and chalcophile elements ratios such as Ni/Co, Cu/Ga, and Ir/Au vary systematically with decreasing metal content of the melt. Surprisingly small (˜102) effective metal/silicate‐melt distribution coefficients for highly siderophile elements probably reflect inefficient segregation of metal despite the large degrees of melting. Moderately volatile lithophile elements such K and Rb were mobilized and heterogeneously distributed in the L‐chondrite impact breccias whereas highly volatile elements such as Cs and Pb were profoundly depleted in the region of the parent body sampled by Chico. Volatile element variations in Chico and other L chondrites are more consistent with a mechanism related to impact heating rather than condensation from a solar nebula. Impact processing can significantly alter the primary distributions of siderophile and volatile elements in chondritic planetesimals.

  DOI：

  10.1111/j.1945-5100.2002.tb00820.x