2-{2-[2-(2-{2-[2-(chlorocarbonyl)phenoxy]ethoxy}ethoxy)ethoxy]ethoxy}-1-benzenecarbonyl chloride | 343806-07-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-{2-[2-(2-{2-[2-(chlorocarbonyl)phenoxy]ethoxy}ethoxy)ethoxy]ethoxy}-1-benzenecarbonyl chloride
• 英文别名: 2-[2-[2-[2-[2-(2-carbonochloridoylphenoxy)ethoxy]ethoxy]ethoxy]ethoxy]benzoyl chloride
• CAS: 343806-07-5
• 化学式: C₂₂H₂₄Cl₂O₇
• 分子量: 471.334
• InChiKey: DFWCFABZGKIOOQ-UHFFFAOYSA-N

物化性质

• 沸点：
  572.3±50.0 °C(Predicted)
• 密度：
  1.276±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.95
• 重原子数：
  31.0
• 可旋转键数：
  16.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  80.29
• 氢给体数：
  0.0
• 氢受体数：
  7.0

反应信息

• 作为反应物：
  描述：

  2,6-二氨基吡啶 、 2-{2-[2-(2-{2-[2-(chlorocarbonyl)phenoxy]ethoxy}ethoxy)ethoxy]ethoxy}-1-benzenecarbonyl chloride 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 0.33h， 以95%的产率得到10,13,16,19,22-pentaoxa-2,30,35-triazatetracyclo[29.3.1.0^4,9.0^23,28]pentatriaconta-1(35),4(9),5,7,23,25,27,31,33-nonaene-3,29-dione
  参考文献：
  名称：

  Rahimizadeh; Eshghi; Rostami, Polish Journal of Chemistry, 2005, vol. 79, # 1, p. 73 - 81

  摘要：

  DOI：
• 作为产物：
  描述：

  1-溴-2-(2-(2-(2-溴乙氧基)乙氧基)乙氧基)乙烷 在 sodium hydroxide 、 氯化亚砜 、 potassium carbonate 作用下， 以 水 、 丙酮 为溶剂， 反应 196.0h， 生成 2-{2-[2-(2-{2-[2-(chlorocarbonyl)phenoxy]ethoxy}ethoxy)ethoxy]ethoxy}-1-benzenecarbonyl chloride
  参考文献：
  名称：

  Rahimizadeh; Eshghi; Rostami, Polish Journal of Chemistry, 2005, vol. 79, # 1, p. 73 - 81

  摘要：

  DOI：

文献信息

• Sieger, Heinz; Voegtle, Fritz, Liebigs Annalen der Chemie, 1980, # 3, p. 425 - 440
  作者：Sieger, Heinz、Voegtle, Fritz

  DOI：——

  日期：——
• New Fluorimetric Alkali and Alkaline Earth Metal Cation Sensors Based on Noncyclic Crown Ethers by Means of Intramolecular Excimer Formation of Pyrene
  作者：Yoshio Suzuki、Tatsuya Morozumi、Hiroshi Nakamura、Masatsugu Shimomura、Takashi Hayashita、Richard A. Bartsh

  DOI：10.1021/jp981567t

  日期：1998.10.1

  New fluorescent reagents, 2,2'-[oxybis(3-oxapentamethyleneoxy)]-bis[N(1-pyrenylmethyl)benzamide)] (4) and its analogues (2, 3, and 5) which have two pyrenes at the both terminals of polyoxyethylene compounds, were synthesized, and their complexation behavior with alkaline earth cations was investigated by fluorescence spectrometry, fluorescence lifetimes, and H-1 NMR spectrometry. These reagents (3-5) showed strong intramolecular excimer emissions around at 480 nm in the fluorescence spectra. On the complexation with alkaline earth metal cations, the increase of monomer emission around at 400 nm accompanied by the disappearance of intramolecular excimer emission of free reagents was observed. These reagents formed a 1:1 complex, and the order of complex formation constants was Ca2+ congruent to Sr2+ > Ba2+ > Mg2+ > Li+ for all reagents. H-1 NMR spectra of these complexes with alkaline earth cations suggested the helical structures of the complexes. Fluorescence spectral changes at the formation of complexes depended on the chain length of the oxyethylene moiety and metal cations. In all cases, the formation of helical structures at the complexation was supported by the H-1 NMR spectra.
• Synthesis and Photopysical Properties of a Polioxo Ethylene Chain Alkaline Earth Metal Fluorescent Sensor with 2-Aminoanthracene As Terminal Group
  作者：Chan Xu、Weisheng Liu、Wenwu Qin

  DOI：10.1021/jp200514u

  日期：2011.5.5

  A new symmetric polioxo ethylene chain fluorescent probe containing 2-aminoanthracene bichromophoric as the terminal group for the alkaline earth metal cation, 2,2'-[oxybis(3-oxapentamethyleneoxy)]-bis[N-(2-anthryl)benzamide)] (1), has been synthesized. The photo-physical properties of 1 have been studied by means of absorption, fluorescence spectroscopy, and H-1 NMR. The difference in emission spectra response to concentration of model compound 2-acetamido-anthracene and 1 in acetonitrile implies that intermolecular excited dimers is likely to occur. Fluorescence decay profiles of 2-acetamido-anthracene can be described by a biexponential fit, while three lifetimes, two of which are similar as those of 2-acetamido-anthracene, are found for 1. The third lifetime might be attributed to intramolecular excited dimers. Complex formation with alkaline earth metal ions are investigated in acetonitrile as solvent via fluorimetric titrations. Fluorescence intensity trend of the complex with Mg2+ differed from those of other alkaline earth metal ions. The compound forms 1:2 (ligand/Mg2+) complex with Mg2+ while formed 1:1 complexes with Ca2+, Sr2+, and Ba2+, producing large hypochromic shifts in the emission spectra and significant cation-induced fluorescence amplifications. On the contrary, the addition of Ca2+, Sr2+, or Ba2+ lead to a decrease in the fluorescence emission first, then an increase and blue shift in emission could be found at the end.
• SIEGER H.; VOEGTLE F., LIEBIGS ANN. CHEM., 1980, NO 3, 425-440
  作者：SIEGER H.、 VOEGTLE F.

  DOI：——

  日期：——