4,4-difluoro-3,5-diphenyl-8-trifluoromethyl-4-bora-3a,4a-diaza-s-indacene | 1298108-69-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 4,4-difluoro-3,5-diphenyl-8-trifluoromethyl-4-bora-3a,4a-diaza-s-indacene
• CAS: 1298108-69-6
• 化学式: C₂₂H₁₄BF₅N₂
• 分子量: 412.17
• InChiKey: CWTJCMOJSUKOIU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
  None
• 氢给体数：
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• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  2-苯基-吡咯 在 吡啶 、 sodium tetrahydroborate 、 四磷十氧化物 、 碳酸氢钠 、 2,3-二氯-5,6-二氰基-1,4-苯醌 作用下， 以 甲醇 、 乙醚 、 二氯甲烷 为溶剂， 反应 5.34h， 生成 4,4-difluoro-3,5-diphenyl-8-trifluoromethyl-4-bora-3a,4a-diaza-s-indacene
  参考文献：
  名称：

  General Route to Symmetric and Asymmetric meso-CF₃-3(5)-Aryl(hetaryl)- and 3,5-Diaryl(dihetaryl)-BODIPY Dyes

  摘要：

  A general efficient route to hitherto inaccessible symmetric and asymmetric meso-CF3-BODIPY dyes has been developed. The key stages Include the reduction of available 2-trifluoroacetylpyrroles to the corresponding alcohols which are further condensed with pyrroles. The method allows the BODIPY with 3(5)aryl(hetaryl) and 3,5-diaryl(hetaryl) substituents to be readily assembled. The BODIPY dyes synthesized fluoresce (Phi(f) = 0.56-1.00) in the 560-680 nm region.

  DOI：

  10.1021/ol200360f

文献信息

• General Route to Symmetric and Asymmetric <i>meso</i>-CF₃-3(5)-Aryl(hetaryl)- and 3,5-Diaryl(dihetaryl)-BODIPY Dyes
  作者：Lubov N. Sobenina、Alexander M. Vasil’tsov、Olga V. Petrova、Konstantin B. Petrushenko、Igor A. Ushakov、Gilles Clavier、Rachel Meallet-Renault、Albina I. Mikhaleva、Boris A. Trofimov

  DOI：10.1021/ol200360f

  日期：2011.5.20

  A general efficient route to hitherto inaccessible symmetric and asymmetric meso-CF3-BODIPY dyes has been developed. The key stages Include the reduction of available 2-trifluoroacetylpyrroles to the corresponding alcohols which are further condensed with pyrroles. The method allows the BODIPY with 3(5)aryl(hetaryl) and 3,5-diaryl(hetaryl) substituents to be readily assembled. The BODIPY dyes synthesized fluoresce (Phi(f) = 0.56-1.00) in the 560-680 nm region.