(9Z)-9-[(4-methoxyphenyl)methylidene]indeno[2,1-b]pyridine | 80499-49-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: (9Z)-9-[(4-methoxyphenyl)methylidene]indeno[2,1-b]pyridine
• CAS: 80499-49-6
• 化学式: C₂₀H₁₅NO
• 分子量: 285.345
• InChiKey: UUHSQQIZZZFJEQ-UYRXBGFRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  22
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  22.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  9H-茚并[2,1-b]吡啶 、 4-甲氧基苯甲醛 在 potassium ethoxide 作用下， 以 乙醇 为溶剂， 以13%的产率得到(9E)-9-[(4-methoxyphenyl)methylidene]indeno[2,1-b]pyridine
  参考文献：
  名称：

  Prostakov, N. S.; Fedorov, V. O.; Soldatenkov, A. T., Journal of Organic Chemistry USSR (English Translation), 1980, vol. 16, p. 2031 - 2033

  摘要：

  DOI：

文献信息

• Prostakov, N. S.; Fedorov, V. O.; Soldatenkov, A. T., Journal of Organic Chemistry USSR (English Translation), 1980, vol. 16, p. 2031 - 2033
  作者：Prostakov, N. S.、Fedorov, V. O.、Soldatenkov, A. T.

  DOI：——

  日期：——
• PROSTAKOV N. S.; FEDOROV V. O.; SOLDATENKOV A. T., ZH. ORGAN. XIMII, 1980, 16, HO 11, 2373-2375
  作者：PROSTAKOV N. S.、 FEDOROV V. O.、 SOLDATENKOV A. T.

  DOI：——

  日期：——
• Synthesis and structural assignment of 2,4′-disubstituted benzylidenefluorenes and 4′-substituted benzylidene-1-azafluorenes
  作者：Rita Annunziata、Valentina Molteni、Laura Raimondi

  DOI：10.1002/(sici)1097-458x(199807)36:7<520::aid-omr327>3.0.co;2-7

  日期：1998.7

  In the course of a study aimed at the investigation of edge-to-face arene-arene interactions, substituted benzylidenefluorenes 8-16 and benzylidene-1-azafluorenes 20-24 were synthesized as mixtures of E-Z-isomers. The full structural assignment of these compounds, performed by 2D NMR experiments, is described together with a study of their E-Z isomerization under equilibrating conditions. For compounds 8-16 no correlation was observed between the electron-donating or electron-withdrawing nature of the substituent groups and the E/Z equilibrium ratios. In the case of 20-24 the predominance of the E-isomers seems to depend exclusively on the N-lone pair-benzylidene ring electronic repulsion rather than on the nature of the pala substituent on the aromatic ring. (C) 1998 John Wiley & Sons, Ltd.