4-bromo-2-cyclopropyl-7-methoxypyrazolo[1,5-a]pyridine | 1219130-41-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡唑并吡啶类
• 英文名称: 4-bromo-2-cyclopropyl-7-methoxypyrazolo[1,5-a]pyridine
• CAS: 1219130-41-2
• 化学式: C₁₁H₁₁BrN₂O
• 分子量: 267.125
• InChiKey: PVSKREKYZIWOKF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  26.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• HETEROCYCLIC BIARYL DERIVATIVE AND PDE INHIBITOR COMPRISING SAME AS ACTIVE INGREDIENT
  申请人：Kohno Yasushi

  公开号：US20110178041A1

  公开（公告）日：2011-07-21

  Novel heterocyclic biaryl derivatives were disclosed which are useful as pharmaceutical agents and which exhibit a phosphodiesterase-inhibitory action. The heterocyclic biaryl derivatives are represented by the following general formula (1): wherein the Heterocycle 1 and the Heterocycle 2 are directly bonded together.

  揭示了一种新颖的杂环双芳基衍生物，可用作药物，并表现出磷酸二酯酶抑制作用。这些杂环双芳基衍生物由以下一般式（1）表示： 其中杂环1和杂环2直接连接在一起。
• ISOQUINOLINE DERIVATIVE, AND PDE INHIBITOR COMPRISING SAME AS ACTIVE INGREDIENT
  申请人：Kohno Yasushi

  公开号：US20110224250A1

  公开（公告）日：2011-09-15

  The present invention provides a novel isoquinoline derivative which is useful as a pharmaceutical agent having a phosphodiesterase inhibitory activity. The isoquinoline derivative of the present invention is represented by the following general formula (1):

  本发明提供了一种新型的异喹啉衍生物，其作为一种具有磷酸二酯酶抑制活性的药物剂使用。本发明的异喹啉衍生物由下列通式（1）表示：
• HETEROCYCLIC BIARYL DERIVATIVE, AND PDE INHIBITOR COMPRISING SAME AS ACTIVE INGREDIENT
  申请人：Kyorin Pharmaceutical Co., Ltd.

  公开号：EP2348018A1

  公开（公告）日：2011-07-27

  Novel heterocyclic biaryl derivatives were disclosed which are useful as pharmaceutical agents and which exhibit a phosphodiesterase-inhibitory action. The heterocyclic biaryl derivatives are represented by the following general formula (1): wherein the Heterocycle 1 and the Heterocycle 2 are directly bonded together.

  已公开的新型杂环双芳基衍生物可用作药剂，并具有抑制磷酸二酯酶的作用。 这些杂环双芳基衍生物由以下通式(1)表示： 其中杂环 1 和杂环 2 直接结合在一起。