bis(triphenylphosphine)palladium(II)-chloride

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: bis(triphenylphosphine)palladium(II)-chloride
• 英文别名: bis(triphenylphosphine)palladium(II) dichloride；PdCl2(PPh3)2；Pd(PPh3)2Cl2；bistriphenylphosphine palladium dichloride；palladium;triphenylphosphane;dihydrochloride
• 化学式: C₃₆H₃₂Cl₂P₂Pd
• 分子量: 703.924
• InChiKey: ILBDOZRDKNIJBS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.73
• 重原子数：
  41
• 可旋转键数：
  6
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0
• 氢给体数：
  2
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  bis(triphenylphosphine)palladium(II)-chloride 、 4-(4-bromophenyl)-1-ethoxycarbonyl-2-(2,6-difluorophenyl)-4,5-dihydro-1H-imidazole 、 4-三氟甲氧基苯硼酸 在 sodium carbonate 作用下， 以 乙二醇二甲醚 为溶剂， 生成 1-ethoxycarbonyl4-(4'-trifluoromethoxy-4-biphenylyl)-2-(2,6-difluoro-phenyl)-4,5-dihydro-1H-imidazole
  参考文献：
  名称：

  Diphenylimidazolines

  摘要：

  这项发明涉及到公式（I）中的新型二苯基咪唑啉化合物，其中Ar1、Ar2和R在描述中各自定义，并提供了多种制备这些化合物的方法以及它们用于控制动物害虫的用途。

  公开号：

  US06380237B1
• 作为试剂：
  描述：

  1,4-二氧六环 、 三甲基乙炔基硅 、 5,5'-((sulfonylbis(4,1-phenylene))bis(oxy))bis(1,3-dibromobenzene) 在 bis(triphenylphosphine)palladium(II)-chloride 、 potassium carbonate 、 三乙胺 作用下， 以76 %的产率得到5,5'-((sulfonylbis(4,1-phenylene))bis(oxy))bis(1,3-diethynylbenzene)
  参考文献：
  名称：

  PHOTORESIST UNDERLAYER COMPOSITIONS AND METHODS OF FORMING ELECTRONIC DEVICES

  摘要：

  Photoresist underlayer compositions, comprising: a curable compound comprising a group of the following formula (1): wherein: R 1 is each independently H, C 1-30 alkyl, or C 3-30 cycloalkyl; Ar 1 is an aromatic ring or a fused aromatic ring system having from 5 to 30 carbon atoms, wherein Ar 1 is substituted or unsubstituted; Ar 2 is an aromatic ring chosen from a 6-membered carbocyclic aromatic ring, a 5- or 6-membered heteroaromatic ring, or a fused aromatic ring system having from 5 to 30 carbon atoms, wherein Ar 2 optionally comprises a fused cyclic imide moiety, a fused oxazole moiety, a fused imidazole moiety, or a fused thiazole moiety, and wherein Ar 2 is substituted or unsubstituted; Y 1 is a single covalent bond, or is selected from —O—, —C(O)—, —C(O)O—, —S—, —S(O) 2 —, —N(R 2 )—, —C(O)N(R 2 )—, —C(O)N(R 2 )C(O)—, —(CH 2 ) y —, or a combination thereof, wherein R 2 is H, C 1-10 alkyl, C 2-10 unsaturated hydrocarbyl, C 5-30 aryl, C(O)R 3 , or S(O) 2 R 3 , wherein R 3 is chosen from H, C 1-10 alkyl, C 2-10 unsaturated hydrocarbyl, and C 5-30 aryl, and y is an integer from 1 to 6; x is an integer from 2 to 5; and * denotes a binding site to a part of the curable compound other than the group represented by formula (1), provided that no two groups are in an ortho position to each other on Ar 1 , wherein ** denotes the point of attachment to an aromatic ring carbon of Ar 1 ; and a solvent.

  公开号：

  US20240264528A1

文献信息

• BICYCLIC TRAIZOLE DERIVATIVES FOR TREATING OF TUMORS
  申请人：Stieber Frank

  公开号：US20110135600A1

  公开（公告）日：2011-06-09

  Compounds of the formula (I), in which X 1 , X 2 , X 3 , X 4 , X 5 , R 1 , R 2 , R 3 , R 3′ , R 4 , R 6 and R 7 have the meanings indicated in Claim 1 , are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumours.

  式（I）中的化合物，其中X1，X2，X3，X4，X5，R1，R2，R3，R3'，R4，R6和R7的含义如权利要求书中所示，是酪氨酸激酶的抑制剂，特别是Met激酶，并可用于治疗肿瘤。
• Biphenyl and biphenyl-analogous compounds as integrin antagonists
  申请人：——

  公开号：US20020016461A1

  公开（公告）日：2002-02-07

  The present invention relates to biphenyl and biphenyl-analogous compounds, their preparation and use as pharmaceutical compositions, as integrin antagonists and in particular for the production of pharmaceutical compositions for the treatment and prophylaxis of cancer, arteriosclerosis, restenosis, osteolytic disorders such as osteoporosis and ophthalmic diseases. The compounds according to the invention have the formula ( 1 ) 1 wherein R 1 , R 2 , U, V, A, B, W, R 3 , C and R 4 have the meaning as defined in the claims.

  本发明涉及联苯和类联苯化合物，它们的制备和用作药物组合物，作为整合素拮抗剂，特别用于生产用于治疗和预防癌症、动脉硬化、再狭窄、骨溶解性疾病如骨质疏松和眼科疾病的药物组合物。根据本发明的化合物具有以下式(1)其中R1、R2、U、V、A、B、W、R3、C和R4的含义如权利要求中所定义。
• Diphenylimidazolines
  申请人：Bayer Aktiengesellschaft

  公开号：US06380237B1

  公开（公告）日：2002-04-30

  The invention relates to novel diphenylimidazolines of the formula (I) in which Ar1, Ar2 and R are each as defined in the description, and a plurality of processes for their preparation and to their use for controlling animal pests.

  这项发明涉及到公式（I）中的新型二苯基咪唑啉化合物，其中Ar1、Ar2和R在描述中各自定义，并提供了多种制备这些化合物的方法以及它们用于控制动物害虫的用途。