(S)-2-(((2-hydroxynaphthalen-1-yl)methylene)amino)pentanedioic acid | 162127-21-1

• 分子结构分类: 有机化合物
• 英文名称: (S)-2-(((2-hydroxynaphthalen-1-yl)methylene)amino)pentanedioic acid
• CAS: 162127-21-1
• 化学式: C₁₆H₁₅NO₅
• 分子量: 301.299
• InChiKey: XPHJXXVIQOSGMR-ZDUSSCGKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.28
• 重原子数：
  22.0
• 可旋转键数：
  6.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  107.19
• 氢给体数：
  3.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  nickel(II) chloride hexahydrate 、 (S)-2-(((2-hydroxynaphthalen-1-yl)methylene)amino)pentanedioic acid 、 水 以 乙醇 为溶剂， 反应 1.0h， 生成
  参考文献：
  名称：

  Spectral, Magnetic, Thermal, and DNA Interaction of Ni(II) Complexes of Glutamic Acid Schiff Bases

  摘要：

  Ni(II) complexes with Schiff bases obtained by condensation of glutamic acid with salicylaldehyde; 2,3-; 2,4-; and 2,5-dihydroxybenzaldehyde; and o-hydroxynaphthaldehyde have been synthesized using the template method in ethanol or ammonia media. They were characterized by elemental analyses, conductivity measurements, magnetic moment, UV, IR, and H-1 NMR spectra as well as thermal analysis (TG, DTG, DTA). The Schiff bases are dibasic tridentate or tetradentate donors and the complexes have square planar and octahedral structures. The complexes decompose in two or three steps where kinetic and thermodynamic parameters of the decomposition steps were computed. The interactions of the formed complexes with FM-DNA were monitored by UV and fluorescence spectroscopy.

  DOI：

  10.1080/15533174.2012.684260
• 作为产物：
  描述：

  L-谷氨酸 、 2-羟基-1-萘甲醛 在 sodium hydroxide 、 溶剂黄146 作用下， 以 乙醇 、 水 为溶剂， 反应 2.0h， 生成 (S)-2-(((2-hydroxynaphthalen-1-yl)methylene)amino)pentanedioic acid
  参考文献：
  名称：

  Spectral, Magnetic, Thermal, and DNA Interaction of Ni(II) Complexes of Glutamic Acid Schiff Bases

  摘要：

  Ni(II) complexes with Schiff bases obtained by condensation of glutamic acid with salicylaldehyde; 2,3-; 2,4-; and 2,5-dihydroxybenzaldehyde; and o-hydroxynaphthaldehyde have been synthesized using the template method in ethanol or ammonia media. They were characterized by elemental analyses, conductivity measurements, magnetic moment, UV, IR, and H-1 NMR spectra as well as thermal analysis (TG, DTG, DTA). The Schiff bases are dibasic tridentate or tetradentate donors and the complexes have square planar and octahedral structures. The complexes decompose in two or three steps where kinetic and thermodynamic parameters of the decomposition steps were computed. The interactions of the formed complexes with FM-DNA were monitored by UV and fluorescence spectroscopy.

  DOI：

  10.1080/15533174.2012.684260