| 1253857-49-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四吡咯及其衍生物
• CAS: 1253857-49-6
• 化学式: C₄₇H₆₀N₈NiO₅
• 分子量: 875.734
• InChiKey: HJEFLLMXKNRLGX-WOXBQKIXSA-N

反应信息

• 作为产物：
  描述：

  在 nickel(II) acetate tetrahydrate 作用下， 以 N,N-二甲基甲酰胺 、 氯苯 为溶剂， 反应 14.0h， 以87%的产率得到
  参考文献：
  名称：

  The synthesis and characterisation of carbohydrate-functionalised porphyrazines

  摘要：

  A synthetic pathway to the incorporation of mono- and disaccharide carbohydrate moieties into porphyrazine systems was demonstrated. A range of selectively protected monosaccharide precursors was coupled to a small variety of phthalonitriles, the intermediates were co-macrocyclised to form hybrid porphyrazines in Linstead macrocyclisation reactions Demetallisation of Mg-porphyrazine products was readily effected to afford the free-base pigments, which were subsequently converted into their zinc or nickel complexes Some porphyrazines were deprotected of their isopropylidene groups (on the carbohydrate moieties) under acidic conditions to reveal polar OH groups The extraction coefficients of the porphyrazines between 2-octanol and phosphate buffered saline solution were measured. Comparison of the partition coefficients of the carbohydrate-substituted porphyrazines and their deprotected counterparts revealed that structural alteration offers a way to significantly increase the hydrophilicity of substituted porphyrazines (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.dyepig.2010.05.002