6-methyl-[1,1'-biphenyl]-2,2'-diol | 859079-25-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 6-methyl-[1,1'-biphenyl]-2,2'-diol
• 英文别名: 2-(2-Hydroxyphenyl)-3-methylphenol
• CAS: 859079-25-7
• 化学式: C₁₃H₁₂O₂
• 分子量: 200.237
• InChiKey: LUHXJGDSMBXRAH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-甲基-2'-羟基联苯 在 叔丁基过氧化氢 、 palladium diacetate 、 caesium carbonate 、 三甲基乙酸 作用下， 以 水 、 乙腈 为溶剂， 反应 18.0h， 以50%的产率得到6-methyl-[1,1'-biphenyl]-2,2'-diol
  参考文献：
  名称：

  Synthesis of 2,2′-biphenols through direct C(sp²)–H hydroxylation of [1,1′-biphenyl]-2-ols

  摘要：

  通过Pd（II）催化，tBuOOH氧化和羟基引导的[1,1′-联苯基]-2-醇的C(sp2)–H羟基化反应，已经开发出了一种新的合成方法，可以合成各种取代的2,2′-联苯酚。

  DOI：

  10.1039/c6cc04756d

文献信息

• Rhodium(III)-Catalyzed Cascade Redox-Neutral C-H Functionalization and Aromatization: Synthesis of Unsymmetrical<i>ortho</i>-Biphenols
  作者：Zhiyong Hu、Guixia Liu

  DOI：10.1002/adsc.201601296

  日期：2017.5.17

  An efficient rhodium(III)‐catalyzed coupling reaction of N‐aryloxyacetamides with 6‐diazo‐2‐cyclohexenones through a cascade redox‐neutral C–H functionalization and aromatization has been developed. This novel and scalable transformation provides a straightforward way to construct unsymmetrical ortho‐biphenols with broad substrate scope under mild and redox‐neutral conditions. The synthetic utility

  通过级联氧化还原-中性CH-H官能化和芳构化，已开发出有效的铑（III）催化的N-芳氧基乙酰胺与6-重氮-2-环己酮的偶联反应。这种新颖且可扩展的转化提供了一种在温和和氧化还原中性条件下构建具有广泛底物范围的不对称邻双酚的直接方法。这种方法的合成效用在生物活性化合物的后期功能化和光学活性邻双酚的合成中得到了证明。
• COMPOUND, RESIN, MATERIAL FOR FORMING UNDERLAYER FILM FOR LITHOGRAPHY, COMPOSITION FOR FORMING UNDERLAYER FILM FOR LITHOGRAPHY, UNDERLAYER FILM FOR LITHOGRAPHY, RESIST PATTERN FORMING METHOD, CIRCUIT PATTERN FORMING METHOD, AND PURIFICATION METHOD OF COMPOUND OR RESIN
  申请人：Mitsubishi Gas Chemical Company, Inc.

  公开号：US20180029968A1

  公开（公告）日：2018-02-01

  A compound represented by the following formula (1). (in formula (1), R 1 represents a 2n-valent group having 1 to 30 carbon atoms, R 2 to R 5 each independently represent an alkyl group having 1 to 10 carbon atoms, an aryl group having 6 to 10 carbon atoms, an alkenyl group having 2 to 10 carbon atoms, an alkoxy group having 1 to 30 carbon atoms, a thiol group or a hydroxyl group, provided that at least one R 4 and/or at least one R 5 represents an alkoxy group having 1 to 30 carbon atoms, m 2 and m 3 are each independently an integer of 0 to 8, m 4 and m 5 are each independently an integer of 0 to 9, provided that m 4 and m 5 are not 0 at the same time, n is an integer of 1 to 4, and p 2 to p 5 are each independently an integer of 0 to 2.)

  公式（1）代表的化合物。（在公式（1）中，R1代表具有1至30个碳原子的2n价基团，R2至R5分别独立代表具有1至10个碳原子的烷基基团，具有6至10个碳原子的芳基基团，具有2至10个碳原子的烯烃基团，具有1至30个碳原子的烷氧基团，硫醇基团或羟基团，前提是至少一个R4和/或至少一个R5代表具有1至30个碳原子的烷氧基团，m2和m3分别独立地是0至8的整数，m4和m5分别独立地是0至9的整数，前提是m4和m5不同时为0，n是1至4的整数，p2至p5分别独立地是0至2的整数。）
• [EN] MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES<br/>[FR] MATÉRIAUX POUR DISPOSITIFS ÉLECTROLUMINESCENTS ORGANIQUES
  申请人：MERCK PATENT GMBH

  公开号：WO2017071791A1

  公开（公告）日：2017-05-04

  The present invention relates to compounds comprising a heterocyclic group substituted with a fluoranthene group and a particular aromatic or heteroaromatic group. The compounds are suitable for use in electronic devices, in particular organic electroluminescent devices, comprising these compounds. In some embodiments, the compounds are used as matrix materials for phosphorescent or fluorescent emitters as well as a hole- blocking or an electron-transport layer.

  本发明涉及含有一个杂环基被氟蒽基和一个特定的芳香或杂芳基取代的化合物。这些化合物适用于用于电子设备，特别是包含这些化合物的有机电致发光器件。在某些实施例中，这些化合物被用作磷光或荧光发射体的基质材料，以及阻挡空穴或电子传输层。
• COMPOUND, RESIN, COMPOSITION, RESIST PATTERN FORMATION METHOD, AND CIRCUIT PATTERN FORMATION METHOD
  申请人：Mitsubishi Gas Chemical Company, Inc.

  公开号：US20190010108A1

  公开（公告）日：2019-01-10

  The present invention employs a compound represented by the following formula (0): wherein R Y is a linear, branched, or cyclic alkyl group of 1 to 30 carbon atoms or an aryl group of 6 to 30 carbon atoms; R Z is an N-valent group of 1 to 60 carbon atoms or a single bond; each R T is independently an alkyl group of 1 to 30 carbon atoms optionally having a substituent, an aryl group of 6 to 40 carbon atoms optionally having a substituent, an alkenyl group of 2 to 30 carbon atoms optionally having a substituent, an alkoxy group of 1 to 30 carbon atoms optionally having a substituent, a halogen atom, a nitro group, an amino group, a cyano group, a thiol group, a hydroxy group, or a group in which a hydrogen atom of a hydroxy group is replaced with an acid dissociation group, wherein the alkyl group, the alkenyl group, and the aryl group each optionally contain an ether bond, a ketone bond, or an ester bond, wherein at least one R T is a hydroxy group or a group in which a hydrogen atom of a hydroxy group is replaced with an acid dissociation group; X is an oxygen atom, a sulfur atom, or not a crosslink; each m is independently an integer of 0 to 9, wherein at least one m is an integer of 1 to 9; N is an integer of 1 to 4, wherein when N is an integer of 2 or larger, N structural formulas within the parentheses [ ] are the same or different; and each r is independently an integer of 0 to 2.

  本发明采用以下式（0）所代表的化合物：其中RY是1到30个碳原子的直链、支链或环烷基基团，或者是6到30个碳原子的芳基基团；RZ是1到60个碳原子的N价基团或者是一个单键；每个RT独立地是1到30个碳原子的烷基基团，可选地带有取代基，是6到40个碳原子的芳基基团，可选地带有取代基，是2到30个碳原子的烯基基团，可选地带有取代基，是1到30个碳原子的烷氧基基团，可选地带有取代基，是卤素原子、硝基基团、氨基基团、氰基基团、硫醇基团、羟基或者羟基的氢原子被酸解离基团取代的基团，其中烷基基团、烯基基团和芳基基团每个可选地包含醚键、酮键或酯键，其中至少一个RT是羟基或者羟基的氢原子被酸解离基团取代的基团；X是氧原子、硫原子或者不是交联；每个m独立地是0到9的整数，其中至少一个m是1到9的整数；N是1到4的整数，当N是2或更大的整数时，括号中的N个结构式是相同或不同的；每个r独立地是0到2的整数。
• COMPOUND, RESIN, COMPOSITION AND PATTERN FORMATION METHOD
  申请人：Mitsubishi Gas Chemical Company, Inc.

  公开号：US20210070727A1

  公开（公告）日：2021-03-11

  The present invention provides a compound represented by following formula (0):

  本发明提供了以下式（0）表示的化合物。