(2R)-3-Carboxy-2-[(3-hydroxyhexadecanoyl)oxy]-N,N,N-trimethylpropan-1-aminium | 853681-21-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羟基酸及其衍生物
• 英文名称: (2R)-3-Carboxy-2-[(3-hydroxyhexadecanoyl)oxy]-N,N,N-trimethylpropan-1-aminium
• 英文别名: [(2R)-3-carboxy-2-(3-hydroxyhexadecanoyloxy)propyl]-trimethylazanium
• CAS: 853681-21-7
• 化学式: C23H46NO5+
• 分子量: 416.6
• InChiKey: XKAZIAFZAQAHHG-BPGUCPLFSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  29
• 可旋转键数：
  20
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  83.8
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• COMPOSITIONS AND METHODS FOR PROMOTING HEALTHY NEURAL DEVELOPMENT IN AN UNBORN BABY
  申请人：The Regents of the University of California

  公开号：EP3965820A1

  公开（公告）日：2022-03-16
• THERAPEUTIC SYSTEMS USING MAGNETIC FIELDS
  申请人：University of Iowa Research Foundation

  公开号：US20210052910A1

  公开（公告）日：2021-02-25

  A system may comprise one, two or more magnetic field systems. The magnetic field system may be configured to provide a magnetic field in a first direction to the tissue. The magnetic field system may include at least one magnetic field source to produce the magnetic field. The magnetic field produced by the at least one magnetic field source may include a magnetic field produced by at least one of a permanent magnet, a temporary magnet or electric current flow through a conductor. The same or a second magnetic field system may be configured to provide a second magnetic field in a second direction to the tissue. The magnetic field system may include two or more sources to provide the magnetic field in a second, third or fourth direction that is non-parallel to the first direction.
• METABOLIC PROFILING BY REVERSE-PHASE/ION-EXCHANGE MASS SPECTROMETRY
  申请人：The Board of Trustees of the Leland Stanford Junior University

  公开号：US20210364498A1

  公开（公告）日：2021-11-25

  Disclosed herein are methods of analyzing a biological sample comprising: separating components of the biological sample via reversed-phase (RP) chromatography to obtain an elute; subjecting the elute to separation via ion-exchange (IEX) chromatography or mixed-mode IEX chromatography; and detecting the separated compounds to determine the components of the biological sample. Also disclosed are devices comprising a reversed-phase (RP) chromatography column in communication with an ion-exchange (IEX) chromatography column or mixed-mode IEX chromatography column, wherein there is no switching valve between the columns.
• [EN] COMPOSITIONS AND METHODS FOR PROMOTING HEALTHY NEURAL DEVELOPMENT IN AN UNBORN BABY<br/>[FR] COMPOSITIONS ET MÉTHODES DESTINÉES À FAVORISER UN DÉVELOPPEMENT NEURONAL SAIN CHEZ UN BÉBÉ À NAÎTRE
  申请人：UNIV CALIFORNIA

  公开号：WO2020226683A1

  公开（公告）日：2020-11-12

  Disclosed herein are methods for promoting healthy neural development in an unborn baby, which include administering to a maternal subject gestating the unborn baby a composition or a bacterial composition. Compositions can include trimethylamine N- oxide (TMAO), 5-aminovalerate (5-AV), imidazole propionate (IP), hippurate (HIP), or a combination thereof, and the bacterial compositions can include bacteria of the order Clostridiales. Also disclosed are methods for conditioning a female subject for bringing about offspring with healthy neural development. Additionally disclosed are methods for reducing adverse effects of antibiotic treatment on an unborn baby in a pregnant subject. Also disclosed are methods for selecting a female subject for conditioning to foster healthy neural development in offspring.