2-(1-isobutyl)sulfanylthiocarbonylsulfanyl-2-methylpropionic acid | 874739-79-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-(1-isobutyl)sulfanylthiocarbonylsulfanyl-2-methylpropionic acid
• 英文别名: 2-(1-isobutylsulfanylcarbothionylsulfanyl)-2-methylpropionic acid；2-Methyl-2-(2-methylpropylsulfanylcarbothioylsulfanyl)propanoic acid；2-methyl-2-(2-methylpropylsulfanylcarbothioylsulfanyl)propanoic acid
• CAS: 874739-79-4
• 化学式: C₉H₁₆O₂S₃
• 分子量: 252.423
• InChiKey: GXQJBJDQMQJVJM-UHFFFAOYSA-N

物化性质

• 沸点：
  408.9±24.0 °C(Predicted)
• 密度：
  1.230±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  120
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2-(1-isobutyl)sulfanylthiocarbonylsulfanyl-2-methylpropionic acid 、 1-[2-(2-hydroxyethoxy)ethoxy]-5-[2-(2-methoxyethoxy)ethoxy]naphthalene 在 4-二甲氨基吡啶 、 盐酸-N-乙基-Nˊ-(3-二甲氨基丙基)碳二亚胺 作用下， 以 二氯甲烷 为溶剂， 反应 12.0h， 生成 2-[2-[5-[2-(2-Methoxyethoxy)ethoxy]naphthalen-1-yl]oxyethoxy]ethyl 2-methyl-2-(2-methylpropylsulfanylcarbothioylsulfanyl)propanoate
  参考文献：
  名称：

  LCST: a powerful tool to control complexation between a dialkoxynaphthalene-functionalised poly(N-isopropylacrylamide) and CBPQT4+ in water

  摘要：

  我们描述了萘功能化聚 NIPAM 衍生物 LCST 的应用，它是一种方便、可调且可逆的方法，用于破坏 CBPQT4+ 在水中形成的复合物。

  DOI：

  10.1039/b910856d

文献信息

• Reversible Tethering of Polymers onto Catechol-Based Titanium Platforms
  作者：William Laure、David Fournier、Patrice Woisel、Joël Lyskawa

  DOI：10.1021/acs.langmuir.7b00160

  日期：2017.4.11

  article, we report on the reversible tethering of end-functionalized polymers onto catechol-based titanium platforms by exploiting the reversible Diels–Alder (DA) cycloaddition reaction. For this purpose, furan and maleimide end-functionalized polymers, prepared via reversible addition–fragmentation chain transfer polymerization, were covalently grafted through a DA reaction onto reactive titanium

  在本文中，我们报告了通过利用可逆Diels-Alder（DA）环加成反应将末端官能化聚合物可逆地束缚在基于邻苯二酚的钛平台上。为此，将通过可逆加成-断裂链转移聚合反应制备的呋喃和马来酰亚胺末端官能化聚合物通过DA反应共价接枝到反应性钛平台上，该平台由结合了呋喃或马来酰亚胺部分的邻苯二酚基锚制成。作为概念证明，将亲水性聚（低聚（乙二醇）丙烯酸酯）（POEGA）和疏水性聚（2,2,2-三氟乙基丙烯酸酯）（PTFEA）接枝到钛表面，然后利用热可逆性将其分离DA反应的变化[即，逆Diels-Alder（rDA）]。这些聚合物通过进行第二次DA反应而互换，从而允许根据需要将钛表面的润湿性从疏水性切换为亲水性。呋喃/马来酰亚胺末端官能化的聚合物接枝到官能化（分别为马来酰亚胺/呋喃）的邻苯二酚基钛平台上，随后用于切换钛表面的rDA / DA序列通过衰减的全反射率-傅立叶变换红外光谱法得到证明， X射线光电子能谱和接触角测量。
• Synthesis and Properties of Tetrathiafulvalene End-Functionalized Polymers Prepared via RAFT Polymerization
  作者：Julien Bigot、Bernadette Charleux、Graeme Cooke、François Delattre、David Fournier、Joel Lyskawa、François Stoffelbach、Patrice Woisel

  DOI：10.1021/ma901809a

  日期：2010.1.12

  The reversible addition-fragmentation chain transfer (RAFT) polymerization technique has been employed to synthesize various linear tetrathiafulvalene end-functionalized polymers. n-Butyl acrylate, N-isopropylacrylamide, and styrene monomers were polymerized in the presence of azobis(isobutyronitrile) and a new tetrathiafulvalene (TTF) trithiocarbonate derivative as reversible chain transfer agent. All RAFT polymerizations exhibited pseudo-first-order kinetics, a linear increase of the number-average molar mass (M-n SEC) with conversion and narrow molar mass distributions (polydispersity < 1.3). The resulting homopolymers exhibited alpha-TTF and omega-trithiocarbonyl end groups. Cyclic voltammetry Was Used to investigate the electrochemical properties of the TTF polymers. Finally, we have shown that the TTF moiety at the alpha-chain-end Could be specifically modified by complex formation with the tetracationic cyclophane cyclobis(paraquat-p-phenylene) (CBPQT(4+)) in organic media. Electrochemical oxidation of the TTF moiety resulted in disassembly of the polymer inclusion complex (PIC).
• Functionalization of Titanium Surfaces with Polymer Brushes Prepared from a Biomimetic RAFT Agent
  作者：Cédric Zobrist、Jonathan Sobocinski、Joël Lyskawa、David Fournier、Valérie Miri、Michel Traisnel、Maude Jimenez、Patrice Woisel

  DOI：10.1021/ma200853w

  日期：2011.8.9

  Well-defined dopamine end-functionalized polymers were synthesized by employing the reversible addition fragmentation chain transfer (RAFT) polymerization technique. tert-Butyl acrylate, N-isopropylacrylamide, and styrene monomers were polymerized in the presence of azobis (isobutyronitrile) and a new catechol-based biomimetic RAFT agent incorporating a trithiocarbonate unit. All RAFT polymerizations exhibited pseudofirst-order kinetics, a linear increase of the number-average molar mass (M-n SEC) with conversion and narrow molar mass distributions (polydispersity <1.2). The resulting homopolymers exhibited the electroactive catechol and the omega-trithiocarbonyl end groups. Subsequent immobilization of dopamine end-functionalized polymers on titanium surfaces was monitored by using a surface plasmon resonance (SPR) sensor, and the resulting films were characterized by contact angle, infrared ATR spectroscopy, atomic force microscopy (AFM), and X-ray photoelectron spectroscopy (XPS).
• LCST: a powerful tool to control complexation between a dialkoxynaphthalene-functionalised poly(N-isopropylacrylamide) and CBPQT4+ in water
  作者：Julien Bigot、Marc Bria、Stuart T. Caldwell、Frédéric Cazaux、Alan Cooper、Bernadette Charleux、Graeme Cooke、Brian Fitzpatrick、David Fournier、Joel Lyskawa、Margaret Nutley、François Stoffelbach、Patrice Woisel

  DOI：10.1039/b910856d

  日期：——

  We describe the application of the LCST of a naphthalene-functionalised polyNIPAM derivative as a convenient, tuneable and reversible method to disrupt complex formation with CBPQT4+ in water.

  我们描述了萘功能化聚 NIPAM 衍生物 LCST 的应用，它是一种方便、可调且可逆的方法，用于破坏 CBPQT4+ 在水中形成的复合物。