(3S,4S,5R,6R)-2-methylene-6-((3-oxo-3H-phenoxazin-7-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate | 1356858-95-1

• 分子结构分类: 有机化合物 - 有机杂环化合物
• 英文名称: (3S,4S,5R,6R)-2-methylene-6-((3-oxo-3H-phenoxazin-7-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate
• CAS: 1356858-95-1
• 化学式: C₂₄H₂₁NO₁₀
• 分子量: 483.431
• InChiKey: UPLLTTYUIFFHDW-QPXUXIHVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.34
• 重原子数：
  35.0
• 可旋转键数：
  5.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  140.46
• 氢给体数：
  0.0
• 氢受体数：
  11.0

反应信息

• 作为反应物：
  描述：

  (3S,4S,5R,6R)-2-methylene-6-((3-oxo-3H-phenoxazin-7-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate 在 sodium methylate 作用下， 以 甲醇 为溶剂， 以25 mg的产率得到7-(((2R,3R,4S,5S)-3,4,5-trihydroxy-6-methylenetetrahydro-2H-pyran-2-yl)oxy)-3H-phenoxazin-3-one
  参考文献：
  名称：

  A “Turn-on” Fluorescent Hg²⁺ Chemosensor Based on Ferrier Carbocyclization

  摘要：

  A "turn-on" fluorescent chemosensor with excellent selectivity and satisfactory sensitivity on Hg2+ detection in 100% water media has been established employing a carbohydrate based Ferrier carbocyclization reaction. The probe has also presented satisfactory results for the imaging of Hg2+ ions in cells and organisms.

  DOI：

  10.1021/ol2033477
• 作为产物：
  描述：

  试卤灵 、 2,3,4-Tri-O-acetyl-6-deoxy-6-iodo-α-D-mannopyranosyliodid 在 四丁基溴化铵 、 potassium carbonate 作用下， 以 氯仿 为溶剂， 反应 12.0h， 生成 (3S,4S,5R,6R)-2-methylene-6-((3-oxo-3H-phenoxazin-7-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate
  参考文献：
  名称：

  A “Turn-on” Fluorescent Hg²⁺ Chemosensor Based on Ferrier Carbocyclization

  摘要：

  A "turn-on" fluorescent chemosensor with excellent selectivity and satisfactory sensitivity on Hg2+ detection in 100% water media has been established employing a carbohydrate based Ferrier carbocyclization reaction. The probe has also presented satisfactory results for the imaging of Hg2+ ions in cells and organisms.

  DOI：

  10.1021/ol2033477