N-(2-phenyl-propionyl)-glycine | 65520-59-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-(2-phenyl-propionyl)-glycine
• 英文别名: N-(2-Phenyl-propionyl)-glycin；N-phenylpropionylglycine；2-(2-phenylpropanoylamino)acetic acid
• CAS: 65520-59-4
• 化学式: C₁₁H₁₃NO₃
• 分子量: 207.229
• InChiKey: FBHMOCFYDPRJPI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  66.4
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  聚甘氨酸 、 alkaline earth salt of/the/ methylsulfuric acid 在 alkali 作用下， 生成 N-(2-phenyl-propionyl)-glycine
  参考文献：
  名称：

  Kay; Raper, Biochemical Journal, 1922, vol. 16, p. 470

  摘要：

  DOI：

文献信息

• Small molecule biochemical profiling of individual subjects for disease diagnosis and health assessment
  申请人：Metabolon, Inc.

  公开号：US10267777B2

  公开（公告）日：2019-04-23

  Methods are described herein for small molecule biochemical profiling of an individual subject for diagnosis of a disease or disorder, facilitating diagnosis of a disease or disorder, and/or identifying an increased risk of developing a disease or disorder in the individual subject. Aberrant levels of small molecules present in a sample from an individual subject are identified and diagnostic information relevant to the individual subject is obtained based on the identified aberrant levels. The obtained diagnostic information includes one or more of an identification of at least one biochemical pathway associated with the identified subset of the small molecules having aberrant levels, an identification at least one disease or disorder associated with the identified subset of the small molecules having aberrant levels, and an identification of at least one recommended follow up test associated with the identified subset of the small molecules having aberrant levels.

  本文描述了对个体受试者进行小分子生化分析的方法，以诊断疾病或失调，促进疾病或失调的诊断，和/或确定个体受试者罹患疾病或失调的风险增加。确定个体受试者样本中存在的小分子的异常水平，并根据确定的异常水平获得与个体受试者相关的诊断信息。所获得的诊断信息包括：至少一个生化途径的鉴定，该生化途径与所鉴定的具有异常水平的小分子子集相关；至少一种疾病或紊乱的鉴定，该疾病或紊乱与所鉴定的具有异常水平的小分子子集相关；至少一种推荐的后续检测的鉴定，该检测与所鉴定的具有异常水平的小分子子集相关。
• Automated sample quality assessment
  申请人：Metabolon, Inc.

  公开号：US10890592B2

  公开（公告）日：2021-01-12

  A method of assessing the quality of a biological sample while maintaining the viability of the biological sample for intended use analysis is described herein. The method includes analyzing a biological sample obtained from a subject for an intended use, assessing the quality of the biological sample using one or more biomarkers of sample quality, and simultaneously performing intended use analysis on the same sample. Assessing the quality of the sample can include assessing compliance with sample handling protocols and assessing subject compliance.

  本文描述了一种评估生物样本质量的方法，同时保持生物样本的活力，以便进行预期用途分析。该方法包括分析从受试者处获得的用于预期用途的生物样本，使用一个或多个样本质量生物标志物评估生物样本的质量，并同时对同一样本进行预期用途分析。评估样本质量可包括评估样本处理协议的合规性和评估受试者的合规性。
• ALPHA-AMIDES OF L-AMINO ACIDS AS FRAGRANCE PRECURSORS
  申请人：THE GILLETTE COMPANY

  公开号：EP1047391A1

  公开（公告）日：2000-11-02
• EP1047391A4
  申请人：——

  公开号：EP1047391A4

  公开（公告）日：2005-01-19
• METHODS AND USES FOR METABOLIC PROFILING FOR CLOSTRIDIUM DIFFICILE INFECTION
  申请人：The Board of Regents of The University of Texas System

  公开号：EP2776829A1

  公开（公告）日：2014-09-17