3-(2-Hydroxyethylsulfonyl)-1-morpholin-4-ylpropan-1-one | 1122004-69-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 英文名称: 3-(2-Hydroxyethylsulfonyl)-1-morpholin-4-ylpropan-1-one
• CAS: 1122004-69-6
• 化学式: C₉H₁₇NO₅S
• 分子量: 251.304
• InChiKey: VDXIZFIGSZADQP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  92.3
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Sulfur-containing compound, method of preparation and pharmaceutical uses thereof
  申请人：National Sun Yat-Sen University

  公开号：EP2030968B1

  公开（公告）日：2017-02-22
• SULFUR-CONTAINING COMPOUND, METHOD OF PREPARATION AND PHARMACEUTICAL USES THEREOF
  申请人：NATIONAL SUN YAT-SEN UNIVERSITY

  公开号：US20130172355A1

  公开（公告）日：2013-07-04

  The invention relates to a sulfur-containing compound and the preparation thereof. The invention also relates to the uses of the sulfur-containing compound in inhibiting inducible nitric oxide synthase and/or cyclooxygenase-2 and in treating the diseases associated with inducible nitric oxide synthase and/or cyclooxygenase-2. This invention also describes a series of chemical analogues of the said sulfur-containing compound and the preparation of these compounds.
• PHARMACEUTICAL USES OF SULFUR-CONTAINING COMPOUND
  申请人：NATIONAL SUN YAT-SEN UNIVERSITY

  公开号：US20160009642A1

  公开（公告）日：2016-01-14

  The invention relates to uses of the sulfur-containing compound in inhibiting activities of a factor related to cancer metastasis and/or growth. Preferably, the invention relates to uses of the sulfur-containing compound in inhibiting lung cancer metastasis and/or growth.
• US8722745B2
  申请人：——

  公开号：US8722745B2

  公开（公告）日：2014-05-13
• US9238620B1
  申请人：——

  公开号：US9238620B1

  公开（公告）日：2016-01-19