Design and Facile Solid-Phase Synthesis of Conformationally Constrained Bicyclic Peptoids
摘要:
Triazine-bridged bicyclic peptoids as conformationally constrained peptidomimetics are described. Bicyclic peptoids composed of 6-12 peptoid residues (m, n = 3-6) were synthesized in excellent yields using a highly efficient solid-phase synthetic route.
Design and Facile Solid-Phase Synthesis of Conformationally Constrained Bicyclic Peptoids
摘要:
Triazine-bridged bicyclic peptoids as conformationally constrained peptidomimetics are described. Bicyclic peptoids composed of 6-12 peptoid residues (m, n = 3-6) were synthesized in excellent yields using a highly efficient solid-phase synthetic route.