acetic acid 2-guanylhydrazide hydrochloride | 1309884-92-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: acetic acid 2-guanylhydrazide hydrochloride
• 英文别名: Acetic acid 2-guanyl hydrazide hydrochloride；N-(diaminomethylideneamino)acetamide;hydrochloride
• CAS: 1309884-92-1
• 化学式: C₃H₈N₄O*ClH
• 分子量: 152.584
• InChiKey: YZSJUXUYMZRKHU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.27
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  93.5
• 氢给体数：
  4
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  acetic acid 2-guanylhydrazide hydrochloride 生成 3-氨基-5-甲基-4H-1,2,4-三唑盐酸盐
  参考文献：
  名称：

  Thermodynamic and kinetic aspects of a single-reactor synthesis of 5-amino-3-methyl-1,2,4-triazole hydrochloride from aminoguanidine and acetic acid

  摘要：

  Fundamental thermodynamic and kinetic aspects of the reaction in which acetic acid guanyl hydrazide is formed from aminoguanidine and acetic acid in aqueous solutions at pH 0.6-1.5 and the kinetics of cyclization of acetic acid guanyl hydrazide hydrochloride to 5-amino-3-methyl-1,2,4-triazole hydrochloride in a melt were studied. Methods for synthesis of acetic acid guanyl hydrazide hydrochlorides and 5-amino-3-methyl-1,2,4-triazole hydrochloride were developed.

  DOI：

  10.1134/s1070427211030116
• 作为产物：
  描述：

  肼甲酰亚胺酰胺一氯化氢 、 溶剂黄146 在 盐酸 作用下， 以 水 为溶剂， 生成 acetic acid 2-guanylhydrazide hydrochloride
  参考文献：
  名称：

  Thermodynamic and kinetic aspects of a single-reactor synthesis of 5-amino-3-methyl-1,2,4-triazole hydrochloride from aminoguanidine and acetic acid

  摘要：

  Fundamental thermodynamic and kinetic aspects of the reaction in which acetic acid guanyl hydrazide is formed from aminoguanidine and acetic acid in aqueous solutions at pH 0.6-1.5 and the kinetics of cyclization of acetic acid guanyl hydrazide hydrochloride to 5-amino-3-methyl-1,2,4-triazole hydrochloride in a melt were studied. Methods for synthesis of acetic acid guanyl hydrazide hydrochlorides and 5-amino-3-methyl-1,2,4-triazole hydrochloride were developed.

  DOI：

  10.1134/s1070427211030116