5,6,7,12-tetrahydrodibenzo[c,f][1,5]azastibocine | 1192246-83-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 5,6,7,12-tetrahydrodibenzo[c,f][1,5]azastibocine
• CAS: 1192246-83-5
• 化学式: C₂₁H₂₃F₃NO₃SSb
• 分子量: 548.23
• InChiKey: KJWPOAAJGUEBEJ-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
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• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  以 四氢呋喃 、 乙醚 为溶剂， 生成 5,6,7,12-tetrahydrodibenzo[c,f][1,5]azastibocine
  参考文献：
  名称：

  Synthesis and structure of an air-stable organoantimony complex and its use as a catalyst for direct diastereoselective Mannich reactions in water

  摘要：

  An air-stable organoantimony complex with a 5,6,7,12-tetrahydrodibenzo[c,f][1,5]azastibocine framework was synthesized, characterized, and found to exhibit high catalytic efficiency towards one-pot Mannich reaction with high diastereoselectivity in water. The catalyst can be recycled 10 times without showing any appreciable loss of efficiency. This catalytic system affords a simple and efficient approach for the synthesis of beta-amino ketones. (C) 2010 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2010.03.003
• 作为试剂：
  描述：

  对三氟甲基苯甲醛 、 苯胺 、 苯乙酮 在 5,6,7,12-tetrahydrodibenzo[c,f][1,5]azastibocine 作用下， 以 水 为溶剂， 反应 24.0h， 以70%的产率得到1-phenyl-3-(phenylamino)-3-(4-(trifluoromethyl)-phenyl)propan-1-one
  参考文献：
  名称：

  Synthesis and structure of an air-stable organoantimony complex and its use as a catalyst for direct diastereoselective Mannich reactions in water

  摘要：

  An air-stable organoantimony complex with a 5,6,7,12-tetrahydrodibenzo[c,f][1,5]azastibocine framework was synthesized, characterized, and found to exhibit high catalytic efficiency towards one-pot Mannich reaction with high diastereoselectivity in water. The catalyst can be recycled 10 times without showing any appreciable loss of efficiency. This catalytic system affords a simple and efficient approach for the synthesis of beta-amino ketones. (C) 2010 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2010.03.003