methyl 2-[(5,6-dimethyl-2-sulfido-1,3,4,7,2-dioxadiazaphosphepin-2-yl)amino]-3-phenylpropanoate | 1352955-83-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: methyl 2-[(5,6-dimethyl-2-sulfido-1,3,4,7,2-dioxadiazaphosphepin-2-yl)amino]-3-phenylpropanoate
• CAS: 1352955-83-9
• 化学式: C₁₄H₁₈N₃O₄PS
• 分子量: 355.354
• InChiKey: UGVJTKPTQRZKDM-ZDUSSCGKSA-N

反应信息

• 作为产物：
  描述：

  2-chloro-5,6-dimethyl-1,3,4,7,2-dioxadiazaphosphepine-2-sulfide 、 L-苯丙氨酸甲酯盐酸盐 在 三乙胺 作用下， 以 四氢呋喃 为溶剂， 生成 methyl 2-[(5,6-dimethyl-2-sulfido-1,3,4,7,2-dioxadiazaphosphepin-2-yl)amino]-3-phenylpropanoate
  参考文献：
  名称：

  Synthesis and Bioassay of Alkyl-2-[(5,6-dimethyl-2-sulfido-1,3,4,7,2-dioxadiazaphosphepin-2-yl)amino] Alkyl/Aryl Esters

  摘要：

  Synthesis of alkyl-2-[(5,6-dimethyl-2-sulfido-1,3,4,7,2-dioxadiazaphosphepin-2-yl)amino]alkyl/aryl esters (3a-j) was accomplished via a two-step process. It involves the prior preparation of monochloride intermediate (2) and its subsequent reaction with the amino acid esters in dry tetrahydrofuran in the presence of triethylamine at reflux temperature. These compounds were characterized by infrared (IR), H-1-, C-13-, and P-31-nuclear magnetic resonance (NMR), and mass and elemental analysis and were found to exhibit potent antimicrobial activity.

  DOI：

  10.1080/15533174.2011.591869