| 197730-46-4

• CAS: 197730-46-4；197658-92-7
• 化学式: C₅₉H₅₁MoO₃P₃
• 分子量: 996.913
• InChiKey: AJRUTCUCHDIZIC-FNPPBZBASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  tris(acetonitrile)tricarbonylmolybdenum(0) 、 (2-methyl-2-(((naphthalen-2-ylmethyl)(phenyl)phosphaneyl)methyl)propane-1,3-diyl)bis((naphthalen-2-ylmethyl)(phenyl)phosphane) 以 二氯甲烷 为溶剂， 以93%的产率得到
  参考文献：
  名称：

  Diastereoselectivity in the Reaction of RCH ₂ C[CH ₂ P (Ar)(Lr)] ₃ with Electrophiles: Enhancement of Diastereoselective Control by η ³ ‐Coordination in {RCH ₂ C[CH ₂ P(Ar)(Li) ₃ }Mo(Co) ₃

  摘要：

  AbstractFollowing a procedure developed for H3CC[CH2P(Ph)2]3 (1a) as the starting compound, various tripod ligands RCH2C[CH2P(Ar)2]3 (1) have been transformed into the trilithiotriphosphides RCH2C[CH2P(Ar)(Li)]3 with various electrophiles R′ — Hal leads to the two diastereomers of RCH2C[CH2P‐(Ar)(R)]3 (6) with an (RRR/SSS : RRS/SSR) ratio close to the statistical value of 1:3, except when ArPh and R′Bzl, where the RRS/SSR diastereomer is obtained almost exclusively. In contrast, the reaction of [RCH2C[CH2P(Ar)(Li)[3]‐Mo(CO)3 (4) with electrophiles R′ — Hal tends to favour the formation of the homochiral RRR/SSS diastereomers. The triphosphide coordination compounds 4 are available by two different routes: either the complexes (RCH2C[CH2P‐(Ar)(H)]3Mo(CO)3, obtained from 2 and (CH3CN)3Mo(CO)3, are deprotonated by MeLi, or the trilithiotriphosphides RCH2C[CH2P(Ar)(Li)]3 are reacted with (CH3CN)3Mo(CO)3 to produce 4 in high yields. The ration in which the two diastereomeric forms of 5 are obtained depends on the nature of the electrophile: the greatest diastereomeric discrimination is obtained for ArPh, RPh, R′Bzl, where the homochiral relative to the RRS/SSR pair. Two‐dimensional NMR spectra and simulations of one‐dimensional spectra are used to ascertain the diastereomeric excess in each case. X‐ray analyses of three compounds of type 5 (5d, ArPh, RH, R′Ph, R′Bzl) indicate the remarkable conformational stability of the tripod metal scaffolding, with the conformations observed for these three compounds in three different solid‐state environments being closely similar, even with respect to the torsional arrangement of the phosphorus‐bound benzyl groups.

  DOI：

  10.1002/cber.19971301006