tetramethyl (1H-benzo[d]imidazol-1-yl)methylenediphosphonate | 1269412-98-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: tetramethyl (1H-benzo[d]imidazol-1-yl)methylenediphosphonate
• CAS: 1269412-98-7
• 化学式: C₁₂H₁₈N₂O₆P₂
• 分子量: 348.232
• InChiKey: XMIAFQKXTTUXAE-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  苯并咪唑 、 亚磷酸二甲酯 在 aluminum oxide 、 原甲酸三乙酯 作用下， 反应 0.2h， 以89%的产率得到tetramethyl (1H-benzo[d]imidazol-1-yl)methylenediphosphonate
  参考文献：
  名称：

  Green Synthesis of Aminobisphosphonates Under Microwave Irradiation

  摘要：

  A simple, efficient, and environmentally benign green chemical method has been developed for the synthesis of aminobisphosphonates by reacting aliphatic/aromatic 2 degrees-amines, dimethylphosphite, and triethylorthoformate by microwave irradiation under solvent-free conditions, in the presence of an alumina solid support. The advantages of this method are less reaction time, simple work-up, and excellent yields. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file. GRAPHICAL ABSTRACT[image omitted].

  DOI：

  10.1080/10426507.2010.482542