2-ethyl-2,5-dihydrothiophen | 53101-74-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氢噻吩类
• 英文名称: 2-ethyl-2,5-dihydrothiophen
• 英文别名: 2-ethyl-2,5-dihydrothiophene
• CAS: 53101-74-9
• 化学式: C₆H₁₀S
• 分子量: 114.211
• InChiKey: OFUIYIHUYQMFTK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  7
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  25.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  溴化乙烯基三苯基膦 、 4-ethyl-2-(1-sulfanylpropyl)-1,3-oxathiolan-5-ol 在 三乙胺 作用下， 以 吡啶 为溶剂， 反应 14.0h， 以75%的产率得到2-ethyl-2,5-dihydrothiophen
  参考文献：
  名称：

  McIntosh, John M.; Siddiqui, Maqbool A., Canadian Journal of Chemistry, 1983, vol. 61, p. 1872 - 1875

  摘要：

  DOI：

文献信息

• Hydrogenation of thiophens via the consecutive electron and proton transfer to thiophenium ions
  作者：Yury Lyakhovetsky、Michael Kalinkin、Zinaida Parnes、Flura Latypova、Dmytry Kursanov

  DOI：10.1039/c39800000766

  日期：——

  Thiophen and 2-ethylthiophen are hydrogenated to the corresponding 2,5-dihydrothiophens with Zn and CF3CO2H via a mechanism involving the protonation of the thiophen ring to the respective thiophenium ion, followed by the transfer of two electrons from Zn and the second proton from the acid.

  噻吩和2-乙基噻吩通过涉及将噻吩环质子化为相应的噻吩离子的机理，随后通过Zn和CF 3 CO 2 H的质子化作用，与Zn和CF 3 CO 2 H氢化为相应的2,5-二氢噻吩。来自酸的第二个质子。
• Reduction of thiophenes in the presence of sulfuric acid and zinc
  作者：F. M. Latypova、M. A. Parfenova、N. K. Lyapina

  DOI：10.1007/s10593-011-0877-y

  日期：2011.12

  Alkyl-substituted thiophenes are hydrogenated by the Zn-H2SO4 system to the corresponding 2,5-dihydrothiophenes and thiophanes. In the case of 2-formyl-and 2-acetylthiophene it was established that in substituted thiophenes simultaneous reduction of the substituent to an alkyl group occurs in addition to hydrogenation of the aromatic ring. The optimum conditions for hydrogenation were selected experimentally.
• Lyakhovetskii, Yu. I.; Latypova, F. M.; Lyapina, N. K., Journal of Organic Chemistry USSR (English Translation), 1992, vol. 28, # 6.2, p. 1001 - 1010
  作者：Lyakhovetskii, Yu. I.、Latypova, F. M.、Lyapina, N. K.、Parnes, Z. N.

  DOI：——

  日期：——
• Hydrogenation of substituted thiophenes by the Zn-H2SO4 system
  作者：F. M. Latypova、Yu. I. Lyakhovetskii、N. K. Lyapina、Z. N. Parnes

  DOI：10.1007/bf00956123

  日期：1985.6
• Hydrogenation of alkylthiophenes by the Zn-TsOH-H2O/AlHal3 system
  作者：F. M. Latypova、Yu. I. Lyakhovetskii、N. K. Lyapina、Z. N. Farnes

  DOI：10.1007/bf00954057

  日期：1986.9