tetrachloro-2-(chloromethyl)pyridine | 37665-07-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: tetrachloro-2-(chloromethyl)pyridine
• 英文别名: 2,3,4,5-Tetrachloro-6-(chloromethyl)pyridine
• CAS: 37665-07-9
• 化学式: C₆H₂Cl₅N
• 分子量: 265.354
• InChiKey: HCELSFXRWARYCZ-UHFFFAOYSA-N

物化性质

• 熔点：
  55.5-60 °C
• 沸点：
  296.0±35.0 °C(Predicted)
• 密度：
  1.677±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  tetrachloro-2-(chloromethyl)pyridine 在 三氯化铝 、 氯 作用下， 以 四氯化碳 为溶剂， 反应 19.0h， 生成 tetrachloro-2-(α,α-dichlorobenzyl)pyridine
  参考文献：
  名称：

  Monofunctionalized tridecachlorodiphenyl (2-pyridyl)methyl radicals. Synthesis and spectral analysis

  摘要：

  Highly chlorinated diphenyl(2-pyridyl)methyl radicals and their alpha-H precursors with a carboxy, chlorocarbonyl, or allyloxycarbonyl substituent in the 4-position of one phenyl ring have been synthesized. All of them are stable red solids, completely dissociated (magnetic susceptibility), decomposing when melting (200-240-degrees-C). Their ESR, UV-VIS and IR spectra are given.

  DOI：

  10.1039/p19910001101
• 作为产物：
  描述：

  3,4,5,6-tetrachloro-2-methylpyridine 在 氯 作用下， 以 四氯化碳 为溶剂， 反应 0.5h， 以60.5%的产率得到tetrachloro-2-(chloromethyl)pyridine
  参考文献：
  名称：

  Monofunctionalized tridecachlorodiphenyl (2-pyridyl)methyl radicals. Synthesis and spectral analysis

  摘要：

  Highly chlorinated diphenyl(2-pyridyl)methyl radicals and their alpha-H precursors with a carboxy, chlorocarbonyl, or allyloxycarbonyl substituent in the 4-position of one phenyl ring have been synthesized. All of them are stable red solids, completely dissociated (magnetic susceptibility), decomposing when melting (200-240-degrees-C). Their ESR, UV-VIS and IR spectra are given.

  DOI：

  10.1039/p19910001101

文献信息

• Process for preparing 2,3,4,5-tetrachloro-6 (trichloro methyl) pyridine
  申请人：MAKHTESHIM CHEMICAL WORKS LIMITED

  公开号：EP0283531A1

  公开（公告）日：1988-09-28

  Heptachloropicoline is prepared by continuously reacting chlorine in the gas phase at an elevated temperature with one or more lower-chlorinated 6-trichloromethyl pyridines in the presence of an effective amount of ferric chloride.

  七氯吡啶啉是通过气相中的氯在高温下与一种或多种低氯 6-三氯甲基吡啶在有效量的氯化铁存在下连续反应制备而成。
• JULIA, LUIS;RIERA, JUAN;TEIXIDO, RAMON, J. CHEM. SOC. PERKIN TRANS. I ,(1991) N, C. 1101-1105
  作者：JULIA, LUIS、RIERA, JUAN、TEIXIDO, RAMON

  DOI：——

  日期：——
• US4801716A
  申请人：——

  公开号：US4801716A

  公开（公告）日：1989-01-31
• Monofunctionalized tridecachlorodiphenyl (2-pyridyl)methyl radicals. Synthesis and spectral analysis
  作者：Luis Julia、Juan Riera、Ramón Teixidó

  DOI：10.1039/p19910001101

  日期：——

  Highly chlorinated diphenyl(2-pyridyl)methyl radicals and their alpha-H precursors with a carboxy, chlorocarbonyl, or allyloxycarbonyl substituent in the 4-position of one phenyl ring have been synthesized. All of them are stable red solids, completely dissociated (magnetic susceptibility), decomposing when melting (200-240-degrees-C). Their ESR, UV-VIS and IR spectra are given.