PPBF | 778599-57-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: PPBF
• 英文别名: phenyl 2,2,4,6,7-pentamethyl-3H-1-benzofuran-5-sulfonate
• CAS: 778599-57-8
• 化学式: C₁₉H₂₂O₄S
• 分子量: 346.447
• InChiKey: STRIAHXBNUPHSK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  61
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  Fmoc-Pbf-L-精氨酸 、 苯酚 在 三氟乙酸 作用下， 以 氯仿 为溶剂， 生成 PPBF
  参考文献：
  名称：

  [EN] METHODS AND COMPOSITIONS FOR IMMUNOMODULATION
  [FR] METHODES ET COMPOSITIONS D'IMMUNOMODULATION

  摘要：

  公开号：

  WO2005037223A3

文献信息

• Multi-subunit vaccines to elicit both MHC- and CD1-restricted T cell responses
  申请人：Northwestern University

  公开号：US11202823B2

  公开（公告）日：2021-12-21

  Provided herein are subunit vaccine compositions comprising a nanocarrier and a lipid antigen, a peptide antigen or combinations thereof that elicit bother a CD1-restricted and an MHC-restricted T cell response in a subject. Methods for making and using the subunit vaccine compositions are also provided.

  本文提供的亚单位疫苗组合物包含纳米载体和脂质抗原、肽抗原或其组合，可在受试者体内引起 CD1 限制性和 MHC 限制性 T 细胞反应。此外，还提供了制造和使用亚单位疫苗组合物的方法。
• MULTI-SUBUNIT VACCINES TO ELICIT BOTH MHC- AND CD1-RESTRICTED T CELL RESPONSES
  申请人：Northwestern University

  公开号：US20200316186A1

  公开（公告）日：2020-10-08

  Provided herein are subunit vaccine compositions comprising a nanocarrier and a lipid antigen, a peptide antigen or combinations thereof that elicit bother a CD1-restricted and an MHC-restricted T cell response in a subject. Methods for making and using the subunit vaccine compositions are also provided.
• REMOTE MODULATION OF BICONTINUOUS NANOSPHERES FOR CONTROLLED DELIVERY APPLICATIONS
  申请人：Northwestern University

  公开号：US20210308065A1

  公开（公告）日：2021-10-07

  Provided herein are bicontinuous nanosphere nanocarrier that allow for slow, sustained release or allow for targeted release of target molecules. Further embodiments of the present invention provide bicontinuous nanosphere nanocarrier comprising a photosensitizer and a suitable polymer. Also provided are methods for making and using the photosensitive nanocarrier.
• US7795242B2
  申请人：——

  公开号：US7795242B2

  公开（公告）日：2010-09-14
• [EN] MULTI-SUBUNIT VACCINES TO ELICIT BOTH MHC- AND CD1-RESTRICTED T CELL RESPONSES<br/>[FR] VACCINS À PLUSIEURS SOUS-UNITÉS POUR INDUIRE DES RÉPONSES DE LYMPHOCYTES T RESTREINTES À LA FOIS PAR LE CMH ET CD1
  申请人：UNIV NORTHWESTERN

  公开号：WO2020206307A1

  公开（公告）日：2020-10-08

  Provided herein are subunit vaccine compositions comprising a nanocarrier and a lipid antigen, a peptide antigen or combinations thereof that elicit bother a CD1 -restricted and an MHC-restricted T cell response in a subject. Methods for making and using the subunit vaccine compositions are also provided.