2-(4'-iodo-1,1'-biphenyl-4-yl)naphthalene | 1026991-03-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-(4'-iodo-1,1'-biphenyl-4-yl)naphthalene
• 英文别名: 2-[4-(4-Iodophenyl)phenyl]naphthalene
• CAS: 1026991-03-6
• 化学式: C₂₂H₁₅I
• 分子量: 406.266
• InChiKey: XXOQTSVSTLNFHM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.4
• 重原子数：
  23
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  2-溴萘 、 4,4-二碘联苯 在 (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride 叔丁基锂 、 indium(III) chloride 作用下， 以 正戊烷 、 四氢呋喃 、 乙醚 为溶剂， 反应 19.0h， 以67%的产率得到2-(4'-iodo-1,1'-biphenyl-4-yl)naphthalene
  参考文献：
  名称：

  Synthesis and Characterization of Polyaromatic Compounds Using Tri(naphthyl)indium

  摘要：

  A variety of polyaromatic compounds beating 1- and 2-naphthyl groups were prepared from the reactions of corresponding halides with tri(1- and 2-naphthyl)indium in good to excellent yields. Thermal, photophysical and electrochemical behaviors of carbazoles having naphthyl groups were studied. They have shown to be promising host and hole transporting materials in organic electroluminescence due to their high thermal stability, electrochemical reversibility and wide band gap.

  DOI：

  10.1021/jo800438n

文献信息

• Substituted azoles, anti-viral active ingredient, pharmaceutical composition, method for the production and use thereof
  申请人：Alla Chem, LLC.

  公开号：EP2808325A1

  公开（公告）日：2014-12-03

  The present invention relates to novel azoles, novel antiviral active components of the general formula 1A and a pharmaceutical composition for prophylaxis and treatment of viral diseases, particularly caused by hepatisis C viruses (HCV).

  本发明涉及新型唑类、通式 1A 的新型抗病毒活性成分和一种药物组合物，用于预防和治疗病毒性疾病，特别是由丙型肝炎病毒（HCV）引起的疾病。