basic iron(III) acetate | 16284-30-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: basic iron(III) acetate
• 英文别名: triaquahexaacetato-μ-oxotriiron(III) acetate；[Fe(III)3O(acetate)6(H2O)3]acetate；Iron(3+);oxygen(2-);heptaacetate;trihydrate
• CAS: 16284-30-3
• 化学式: C₂H₃O₂*C₁₂H₂₄Fe₃O₁₆
• 分子量: 650.899
• InChiKey: HINSVSFBPAGNGL-UHFFFAOYSA-G

计算性质

• 辛醇/水分配系数(LogP)：
  -11.31
• 重原子数：
  35
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  285
• 氢给体数：
  3
• 氢受体数：
  18

反应信息

• 作为反应物：
  描述：

  basic iron(III) acetate 在 air 作用下， 以 solid 为溶剂， 生成 iron oxide
  参考文献：
  名称：

  Gefriergetrocknete Acetate von Sr und Fe als reaktive Vorläufer für komplexe Eisen-Strontium-Oxide

  摘要：

  The thermal decomposition of reactive freeze-dried acetate precursors for Sr-Fe-oxides was investigated by means of DTA, TG, mass spectroscopy and X-ray powder diffractometry. In the case of decomposition of Fe(III)-mu-oxo-acetate four superimposed main steps are characterized as release of (a) H2O, (b) acetic acid and ketene (c) methane, ketene and CO2 and (d) acetone and CO2. On careful decomposition, single phase gamma-Fe2O3 can be formed. The decomposition of freeze-dried mixed Fe-Sr-acetates reflects some aspects of the single acetates, but also an interaction between the components. The interactions result in a lower decomposition temperature of Sr-acetate (release of acetone and formation of SrCO3). The decomposition temperature of SrCO3 in the reactive mixture is also lowered. The simultaneous decomposition of SrCO3 and its reaction with the Fe-component results directly in the formation of the expected complex Sr-Fe-oxide.

  DOI：

  10.1023/b:jtan.0000027185.81130.fb
• 作为产物：
  描述：

  ferric hydroxide 、 水 、 溶剂黄146 以 溶剂黄146 为溶剂， 以96%的产率得到basic iron(III) acetate
  参考文献：
  名称：

  A new facile high yield preparative route for mixed-trinuclear acetate clusters

  摘要：

  The cluster compounds [(Fe3O)-O-III(CH3CO2)(6)(H2O)(3)]CH3COO, [(Fe2FeO)-Fe-III-O-II(CH3COO)(6)(H2O)3], [(Fe2CoO)-Co-III-O-II(CH3COO)(6)(H2O)(3)], [(Fe2NiO)-Ni-III-O-II(CH3COO)(6)(H2O)(3)], [(V2FeO)-Fe-III-O-II(CH3COO)(6)(H2O)(3)] and [(V2CoO)-Co-III-O-II(CH3COO)(6)(H2O)(3) were prepared by new synthetic routes. Homometallic clusters can be isolated from a clean reaction between the metal hydroxide and acetic acid. The heterobimetallic compounds were obtained by the reaction of the iron(III) or vanadium(III)-homometallic cluster, in water, with an excess of iron(II), cobalt(II) and nickel(II) acetates. The new route give pure products with much higher yields when compared with the classical methods. The compounds were characterized by atomic absorption and elemental analysis, electrochemistry and IR spectroscopy. (c) 2005 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.inoche.2005.10.023

文献信息

• Synthesis, magnetic properties, and Mössbauer spectra of polynuclear iron carboxylates
  作者：Janet Catterick、Peter Thornton、Brian W. Fitzsimmons

  DOI：10.1039/dt9770001420

  日期：——

  Several carboxylates of iron(II) and iron(III) have been prepared and their magnetic properties and Mössbauer spectra studied. [Fe4(OMe)6(O2CMe)6], [Fe5O(O2CMe)12][O2CMe], and [Fe3(dmf)3O(O2CPh)6][O2CPh]·dmf (dmf = dimethylformamide) are antiferromagnetic but [Fe4O(O2CMe)10] is ferromagnetic. [Fe(O2CMe)2] and [Fe(py)2(O2CMe)2] are magnetically dilute. The iron(III) compounds show Mössbauer spectra typical

  制备了几种铁（II）和铁（III）的羧酸盐，并研究了它们的磁性能和穆斯堡尔谱。[Fe 4（OMe）6（O 2 CMe）6 ]，[Fe 5 O（O 2 CMe）12 ] [O 2 CMe]和[Fe 3（dmf）3 O（O 2 CPh）6 ] [O 2 CPh]·dmf（dmf =二甲基甲酰胺）是反铁磁性的，而[Fe 4 O（O 2 CMe）10 ]是铁磁性的。[Fe（O 2 CMe）2 ]和[Fe（py）2（O 2 CMe） 2 ]被磁稀释。铁（ III）化合物显示出高自旋Fe 3+离子的典型Mössbauer光谱，但[Fe 4 O（O 2 CMe） 10 ]的光谱非常不对称。适当的质谱，浊度和电导性研究以及电子和红外光谱已为表征提供了支持。
• Nanoscale Metal–Organic Framework Overcomes Hypoxia for Photodynamic Therapy Primed Cancer Immunotherapy
  作者：Guangxu Lan、Kaiyuan Ni、Ziwan Xu、Samuel S. Veroneau、Yang Song、Wenbin Lin

  DOI：10.1021/jacs.8b01072

  日期：2018.5.2

  Immunotherapy has become a promising cancer therapy, but only works for a subset of cancer patients. Immunogenic photodynamic therapy (PDT) can prime cancer immunotherapy to increase the response rates, but its efficacy is severely limited by tumor hypoxia. Here we report a nanoscale metal-organic framework, Fe-TBP, as a novel nanophotosensitizer to overcome tumor hypoxia and sensitize effective PDT

  免疫疗法已成为一种有前途的癌症疗法，但仅适用于一小部分癌症患者。免疫原性光动力疗法（PDT）可以启动癌症免疫疗法以提高反应率，但其疗效受到肿瘤缺氧的严重限制。在这里，我们报告了一种纳米级金属有机框架 Fe-TBP，作为一种新型纳米光敏剂，可以克服肿瘤缺氧并使有效的 PDT 敏感，从而启动非炎症肿瘤进行癌症免疫治疗。 Fe-TBP 由铁氧簇和卟啉配体构建而成，并在常氧和缺氧条件下使 PDT 敏化。 Fe-TBP 介导的 PDT 显着提高了抗程序性死亡配体 1 (α-PD-L1) 治疗的疗效，并在结直肠癌小鼠模型中引发远隔效应，导致肿瘤消退 >90%。机制研究表明，Fe-TBP 介导的 PDT 诱导细胞毒性 T 细胞显着肿瘤浸润。
• A Neutral Cluster Cage with a Tetrahedral [Pd₁₂^IIL₆] Framework: Crystal Structures and Host–Guest Studies
  作者：Arvind K. Gupta、Ashok Yadav、Anant Kumar Srivastava、Kormathmadam Raghupathy Ramya、Harshad Paithankar、Shyamapada Nandi、Jeetender Chugh、Ramamoorthy Boomishankar

  DOI：10.1021/ic502798r

  日期：2015.4.6

  A charge-neutral tetrahedral [(Pd3X)(4)L-6] cage assembly built from a trinuclear polyhedral building unit (PBU), [Pd3X](3+), cis-blocked with an imido P(V) ligand, [(NiPr)(3)PO](3-) (X3-), and oxalate dianions (L-2) is reported. Use of benzoate or ferrocene dicarboxylate anions, which do not offer wide-angle chelation as that of oxalate dianions, leads to smaller prismatic clusters instead of polyhedral cage assemblies. The porosity of the tetrahedral cage assembly was determined by gas adsorption studies, which show a higher uptake capacity for CO2 over N-2 and H-2. The tetrahedral cage was shown to encapsulate a wide range of neutral guest solvents from polar to nonpolar such as dimethyl sulfoxide, benzene, dichloromethane, chloroform, carbon tetrachloride, and cyclopentane as observed by mass spectral and single-crystal X-ray diffraction studies. The H-1 two-dimensional diffusion ordered spectroscopy NMR analysis shows that the host and guest molecules exhibit similar diffusion coefficients in all the studied hostguest systems. Further, the tetrahedral cage shows selective binding of benzene, CCl4, and cyclopentane among other solvents from their categories as evidenced from mass spectral analysis. A preliminary density functional theory analysis gave a highest binding energy for benzene among the other solvents that were structurally shown to be encapsulated at the intrinsic cavity of the tetrahedral cage.