hydrazine stearate | 10195-76-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: hydrazine stearate
• 英文别名: Hydrazinstearat；Aminoazanium;octadecanoate
• CAS: 10195-76-3
• 化学式: C₁₈H₃₆O₂*H₄N₂
• 分子量: 316.528
• InChiKey: VTYFBEUGCXDTQK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.15
• 重原子数：
  22
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  89.3
• 氢给体数：
  3
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  油酸 、 alkaline earth salt of/the/ methylsulfuric acid 生成 hydrazine stearate
  参考文献：
  名称：

  Hanus; Vorisek, Collection of Czechoslovak Chemical Communications, vol. 1, p. 226

  摘要：

  DOI：

文献信息

• CNP CYCLIC PEPTIDE, AND MEDICINE, EXTERNAL PREPARATION AND COSMETIC EACH CONTAINING SAID CYCLIC PEPTIDE
  申请人：Igisu Co., Ltd.

  公开号：EP3330280A1

  公开（公告）日：2018-06-06

  The present invention is aimed at providing a novel peptide with quick expression of drug efficacy/effect and long duration of maintaining amelioration, a medicament or an external preparation comprising the same, in particular a prophylactic or therapeutic for dermatitis, skin roughness, rhinitis, alopecia or thinning hair, or a hair growth stimulant, hair growing agent, an antipruritic or a skin-care product, etc. The present invention has reached said object by providing a cyclic peptide having an amino acid sequence expressed by the formula I or a derivative thereof or a pharmaceutically acceptable salt thereof, wherein the amino acid sequence has no peptide bond other than those which are formed between the amino acids constituting the amino acid sequence.

  本发明的目的是提供一种药效/效果表达快、维持改善时间长的新型多肽，以及包含该多肽的药物或外用制剂，特别是皮炎、皮肤粗糙、鼻炎、脱发或头发稀疏的预防或治疗药物，或毛发生长刺激剂、生发剂、止痒剂或护肤品等。本发明通过提供一种具有式 I 所表示的氨基酸序列的环肽或其衍生物或其药学上可接受的盐来达到上述目的，其中该氨基酸序列除了在构成该氨基酸序列的氨基酸之间形成的肽键外没有其他肽键。
• A CNP CYCLIC PEPTIDE AND A MEDICAMENT, EXTERNAL PREPARATION AND COSMETIC CONTAINING THE CYCLIC PEPTIDE
  申请人：Igisu Co., Ltd.

  公开号：EP3689897A1

  公开（公告）日：2020-08-05

  The present invention is aimed at providing a novel peptide with quick expression of drug efficacy/effect and long duration of maintaining amelioration, a medicament or an external preparation comprising the same, in particular a prophylactic or therapeutic for dermatitis, skin roughness, rhinitis, alopecia or thinning hair, or a hair growth stimulant, hair growing agent, an antipruritic or a skin-care product, etc. The present invention has reached said object by providing a cyclic peptide having an amino acid sequence expressed by the formula I or a derivative thereof or a pharmaceutically acceptable salt thereof, wherein the amino acid sequence has no peptide bond other than those which are formed between the amino acids constituting the amino acid sequence.

  本发明的目的是提供一种药效/效果表达快、维持改善时间长的新型多肽，以及包含该多肽的药物或外用制剂，特别是皮炎、皮肤粗糙、鼻炎、脱发或头发稀疏的预防或治疗药物，或毛发生长刺激剂、生发剂、止痒剂或护肤品等。本发明通过提供一种具有式 I 所表示的氨基酸序列的环肽或其衍生物或其药学上可接受的盐来达到上述目的，其中该氨基酸序列除了在构成该氨基酸序列的氨基酸之间形成的肽键外没有其他肽键。