| 1101198-58-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• CAS: 1101198-58-6
• 化学式: C₄₂H₈₀O₅Si
• 分子量: 693.18
• InChiKey: ISSNVBXRUPUDGJ-WGEIWTTOSA-N

反应信息

• 作为反应物：
  描述：

  、 在 4-二甲氨基吡啶 、 苯甲酰氯 、 N,N-二异丙基乙胺 作用下， 以 四氢呋喃 为溶剂， 生成
  参考文献：
  名称：

  结构化雌甾醇：长度和序列的控制

  摘要：

  AbstractUsing ester‐forming reactions such as carbodiimide coupling and a modified Yamaguchi symmetrical anhydride method, a variety of estolides based on 17‐hydroxy oleic and 17‐hydroxy stearic acid have been prepared. These hydroxy fatty acids are produced in good yields from hydrolysis of sophorolipids, which are in turn derived from fermentation of fats and oils. Since the estolides are formed one unit, or ester bond, at a time, their length and sequence can be precisely controlled. The key to this control is the use of protecting groups at either the carboxylic or hydroxy end of the starting hydroxy fatty acids. Two mono‐protected dimers, for example, when combined in a fragment‐condensation approach, give a tetramer with no “contamination” from estolides of other lengths. This methodology opens the way to functionalized estolides, and several variants were prepared: hybrid estolides, containing non‐fatty acid moieties such as amino acids; polymerizable estolides, containing a norbornene unit; and non‐linear estolides that extend from a branched core such as glycerol or pentaerythritol. With the benzoyl chloride‐mediated symmetrical anhydride method, yields for individual coupling steps ranged from 75 to 93%.

  DOI：

  10.1007/s11746-007-1185-7
• 作为产物：
  描述：

  在 phosphate buffer 、 锌 作用下， 生成
  参考文献：
  名称：

  结构化雌甾醇：长度和序列的控制

  摘要：

  AbstractUsing ester‐forming reactions such as carbodiimide coupling and a modified Yamaguchi symmetrical anhydride method, a variety of estolides based on 17‐hydroxy oleic and 17‐hydroxy stearic acid have been prepared. These hydroxy fatty acids are produced in good yields from hydrolysis of sophorolipids, which are in turn derived from fermentation of fats and oils. Since the estolides are formed one unit, or ester bond, at a time, their length and sequence can be precisely controlled. The key to this control is the use of protecting groups at either the carboxylic or hydroxy end of the starting hydroxy fatty acids. Two mono‐protected dimers, for example, when combined in a fragment‐condensation approach, give a tetramer with no “contamination” from estolides of other lengths. This methodology opens the way to functionalized estolides, and several variants were prepared: hybrid estolides, containing non‐fatty acid moieties such as amino acids; polymerizable estolides, containing a norbornene unit; and non‐linear estolides that extend from a branched core such as glycerol or pentaerythritol. With the benzoyl chloride‐mediated symmetrical anhydride method, yields for individual coupling steps ranged from 75 to 93%.

  DOI：

  10.1007/s11746-007-1185-7